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EMBP Antibody (BMK13): sc-59164

 |  Datasheet

(Based on data analysis)

  • EMBP Antibody (BMK13) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against eosinophils of human origin
  • recommended for detection of EMBP irrespective of the stages of eosinophil activation of human origin by WB, IF and IHC(P); also recommended for detection of the 23.8kDa secreted pro-form of PRG2 also known as MBP(Pregnancy associated MBP) and the 13.8kDa mature form found in the matrix of the eosinophil large specific granule
  • See 1 citations for EMBP Antibody (BMK13)
 

See additional EMBP Antibodies.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
EMBP Antibody (BMK13) sc-59164 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EMBP siRNA (h) sc-44577 10 µM $258
EMBP siRNA (h) sc-44577-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EMBP shRNA Plasmid (h) sc-44577-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EMBP shRNA (h) Lentiviral Particles sc-44577-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MEG-01 Cell Lysate sc-2283 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PRG2 5553 11q12.1 NM_002728 P13727
605601
 


The eosinophil major basic protein (EMBP), also designated MBP, PRG2, proteoglycan 2, BMPG, or bone marrow natural killer cell activator, is a constituent of the crystalline core of the eosinophil granule. High levels of the pro-EMBP are present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT) and C3dg. EMBP may influence antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and may play a role in immune hypersensitivity reactions. EMBP stimulates an Src kinase-dependent activation of class I (A) phosphoinositide 3-kinase and, in turn, activation of protein kinase C Ω in neutrophils. EMBP transcription is under regulation by novel combinatorial interactions of GATA-1, PU.1, and C/EBPé isoforms.

EMBP Antibody (BMK13) Product Citations
See how others have used EMBP Antibody (BMK13) and or EMBP Antibody (BMK13) conjugates.


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