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home » Channel Proteins » Sodium/Potassium-ATPase Protein Antibody / Sodium/Potassium-ATPase Protein Antibodies » Na+/K+-ATPase β1 (M17-P5-F11): sc-58627

Na+/K+-ATPase β1 (M17-P5-F11) Antibody: sc-58627

  |  Datasheet
  • mouse monoclonal IgG2a, 200µg/ml
  • raised against lamb Na+/K+-ATPase β1 from kidney tissue of ovine origin
  • recommended for detection of Na+/K+-ATPase β1 of h, canine and ovine origin by WB, IP and IF; non cross-reactive with the β1 or β2 subunits in rat; also reactive with additional species, including canine
 
Additional Sodium/Potassium-ATPase Protein Antibodies ...
 
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Recommended Support Products:
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WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ATP1B1 481 1q24.2 NM_001001787, NM_001677 P05026
 182330
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Na+/K+-ATPase β1 (M17-P5-F11) sc-58627 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Na+/K+-ATPase β1 siRNA (h) sc-36008 10 µM $258
Na+/K+-ATPase β1 (h)-PR sc-36008-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Na+/K+-ATPase β1 shRNA Plasmid (h) sc-36008-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Na+/K+-ATPase β1 shRNA (h) Lentiviral Particles sc-36008-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MDCK Cell Lysate sc-2252 500 µg/200 µl $104
Caki-1 Cell Lysate sc-2224 500 µg/200 µl $104

Na+/K+-ATPase β1 Background Information
The ubiquitously expressed sodium/potassium-ATPase (Na+/K+-ATPase) exists as a oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, å, ∫ and ©, comprise the Na+/K+-ATPase oligomer. The å subunit contains the binding sites for ATP and the cations; the glycosylated ∫ subunit ensures correct folding and membrane insertion of the å subunits. The small © subunit co-localizes with the å subunit in nephron segments, where it increases the affinity of Na+/K+-ATPase for ATP. The ∫ subunit, but not the © subunit, is essential for normal activity of Na+/K+-ATPase.