Glycodelin Background Information Glycodelin (also designated GD, placental protein 14, PP14, progesterone-associated endometrial protein, progestagen-associated endometrial protein, pregnancy-associated endometrial alpha-2 globulin, PAEG or PEG) is a glycoprotein with structural homology to beta-lactoglobulins. Glycodelin is synthesized by the secretory endometrium and decidua during embryo implantation and in the first few weeks of pregnancy. It is expressed in steroid responsive tissues of the female reproductive tract and in the paranucleolar vacuole, which is characteristically present in lobular breast cancer cells (5-7). Glycodelin expression in breast cancer cells is accompanied by the acquisition of a phenotype of organized glandular epithelium (7).
Glycodelin (BTE 001)
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Glycodelin (BTE 001): sc-57511. Immunoperoxidase staining of formalin fixed, paraffin-embedded human endometrium tissue showing cytoplasmic and extracellular staining of glandular cells.
