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- mouse monoclonal IgG2a, 200µg/ml
- raised against amino acids 792-806 of VCP of human origin
- recommended for detection of VCP of mouse, rat and human origin by WB, IP, IF and IHC(P); also reactive with additional species, including porcine
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Ordering Information
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VCP Background Information
Valosin containing protein (VCP), also designated TERA (for transitional endoplasmic reticulum ATPase) or p97, is a member of the AAA family of ATPases, which are involved in a variety of cellular activities. VCP is the mammalian homolog of Saccharomyces cerevisiae Cdc48, a protein essential for the completion of mitiosis in yeast. VCP is thought to be involved in a variety of membrane functions and in the regulation of the cell cycle. It associates with ubiquitinated I˚B-å as well as with the 26S Proteosome, indicating a potential role for VCP in the proteosome-mediated degradation of I˚B-å. |
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VCP (5)
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VCP (5): sc-57492. Western blot analysis of VCP expression in NIH/3T3 (A), MDA-MB-231 (B), HeLa (C), MCF7 (D), A-431 (E) and PC-12 (F) whole cell lysates.
VCP (5): sc-57492. Western blot analysis of VCP expression in non-transfected 293T: sc-117752 (A), human VCP transfected 293T: sc-112114 (B) and NIH/3T3 (C) whole cell lysates. |
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