Welcome to Santa Cruz Biotechnology!
SCBT Home
Home » Membrane Receptors » BMP Receptor Antibodies » BMPR-IB Antibody (N-17): sc-5679

BMPR-IB Antibody (N-17): sc-5679

 |  Datasheet

(Based on data analysis)

  • BMPR-IB Antibody (N-17) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of BMPR-IB of human origin
  • recommended for detection of BMPR-IB of mouse, rat and human origin by WB, IF, IHC(P) and ELISA; also reactive with additional species, including bovine and porcine
  • blocking peptide, sc-5679 P
  • See 12 citations for BMPR-IB Antibody (N-17)
 

See additional BMP Receptor Antibodies including BMP Receptor, BMPR-I, BMPR-IA, BMPR-IB and BMPR-II.

Also see BMPR-IB Inhibitors for functional analysis of cellular responses to BMPR-IB.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
BMPR-IB Antibody (N-17) sc-5679 200 µg/ml $279
BMPR-IB (N-17) P sc-5679 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
BMPR-IB siRNA (h) sc-40218 10 µM $258
BMPR-IB siRNA (m) sc-40219 10 µM $258
BMPR-IB (h)-PR sc-40218-PR 10 µM, 20 µl $23
BMPR-IB (m)-PR sc-40219-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
BMPR-IB shRNA Plasmid (h) sc-40218-SH 20 µg $520
BMPR-IB shRNA Plasmid (m) sc-40219-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
BMPR-IB shRNA (h) Lentiviral Particles sc-40218-V 200 µl $625
BMPR-IB shRNA (m) Lentiviral Particles sc-40219-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DU 145 Cell Lysate sc-2268 500 µg/200 µl $104
LNCaP Cell Lysate sc-2231 500 µg/200 µl $104
PC-3 Cell Lysate sc-2220 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human BMPR1B 658 4q22.3 NM_001203 O00238
 603248
Mouse Bmpr1b 12167 3 H1 P36898
 N/A
 

Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7) (1–4). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines (3). The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain (1,5,6). The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion (1,5).

BMPR-IB Antibody (N-17) Product Citations
See how others have used BMPR-IB Antibody (N-17) and or BMPR-IB Antibody (N-17) conjugates.


12 total citations
Loading citations.
 
BMPR-IB Antibody (N-17) Data
Click on image to enlarge
sc-5679
BMPR-IB (N-17): sc-5679. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing cytoplasmic staining of purkinje cells.
Download
Datasheets
Get Adobe Acrobat Reader