raised against full length native hnRNP M1-4 of human origin
recommended for detection of hnRNP M1-4 of mouse, rat and human origin by WB, IP, ELISA; also reactive with additional species, including bovine and porcine
hnRNP M1-4 Background Information Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription, pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm, such as hnRNP E1 and E2. hnRNP E1 may function in the cytoplasm as a translational regulatory protein, while hnRNP E2 stabilizes mRNA to enhance polioviral mRNA translation. hnRNP M is involved in pre-mRNA splicing and in stress-induced transient splicing arrest.
hnRNP M1-4 (3C181)
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hnRNP M1-4 (3C181): sc-56702. Western blot analysis of hnRNP M1-4 expression in HeLa (A), MDA-MB-231 (B) and ME-180 (C) whole cell lysates and HeLa nuclear extract (D).
hnRNP M1-4 (3C181): sc-56702. Western blot analysis of hnRNP M1-4 expression in HEK293 whole cell lysate.
hnRNP M1-4 (3C181): sc-56702. Western blot analysis of hnRNP M expression in non-transfected 293: sc-110760 (A), human hnRNP M transfected 293: sc-110504 (B) and HeLa (C) whole cell lysates.
