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home » Membrane Receptors » ACTR Antibody / ACTR Antibodies » ACTR-IIB (N-16): sc-5665

ACTR-IIB (N-16) Antibody: sc-5665

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the N-terminus of ACTR-IIB of human origin
  • recommended for detection of ACTR-IIB of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-5665 P
 
Additional ACTR Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ACVR2B 93 3p22.2 NM_001106 Q13705
 602730
Mouse Acvr2b 11481 9 F3 P27040
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
ACTR-IIB (N-16) sc-5665 200 µg/ml $279
ACTR-IIB (N-16) P sc-5665 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ACTR-IIB siRNA (h) sc-40210 10 µM $258
ACTR-IIB siRNA (m) sc-40211 10 µM $258
ACTR-IIB (h)-PR sc-40210-PR 10 µM $23
ACTR-IIB (m)-PR sc-40211-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ACTR-IIB shRNA Plasmid (h) sc-40210-SH 20 µg $520
ACTR-IIB shRNA Plasmid (m) sc-40211-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ACTR-IIB shRNA (h) Lentiviral Particles sc-40210-V 200 µl $625
ACTR-IIB shRNA (m) Lentiviral Particles sc-40211-V 200 µl $625

ACTR-IIB Background Information
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1-6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

ACTR-IIB (N-16) Product Citations
See how others have used ACTR-IIB (N-16): sc-5665 antibody and or ACTR-IIB (N-16) antibody conjugates.


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