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home » Cell Cycle Proteins » CENP Antibody / CENP Antibodies » CENP-E (1H12): sc-56286

CENP-E (1H12) Antibody: sc-56286

  |  Datasheet
  • mouse monoclonal IgG1, 200 µg/ml
  • raised against full length CENP-E of human origin
  • recommended for detection of CENP-E of human origin by WB, IP, IF and ELISA
 
Additional CENP Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CENPE 1062 4q24 NM_001813 Q02224
 117143
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CENP-E (1H12) sc-56286 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CENP-E siRNA (h) sc-37561 10 µM $258
CENP-E (h)-PR sc-37561-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CENP-E shRNA Plasmid (h) sc-37561-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CENP-E shRNA (h) Lentiviral Particles sc-37561-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
A-431 + Calyculin A Cell Lysate sc-2260 500 µg/200 µl $104
K-562 nuclear extract sc-2130 1000 µg $143
A-431 nuclear extract sc-2122 1000 µg $143

CENP-E Background Information
A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. Centromere Protein E, CENP-E, is a kinetochore motor protein that specifies kinetochore binding in mitosis. Both CENP-E and CENP-F are expressed during mitosis where they mediate the G(2) to M phase checkpoint. CENP-E is also expressed in high levels during meiosis I and meiosis II where it localizes to the fibrous corona and outer plate of kinetochores on the meiotic chromosomes. CENP-E colocalizes with hBUBR1, a BUB-related kinase until mid-anaphase. After the first polar body emission, CENP-E localizes to the spindle-midzone, separating from hBUBR1 after mid-anaphase.

CENP-E (1H12) Product Citations
See how others have used CENP-E (1H12): sc-56286 antibody and or CENP-E (1H12) antibody conjugates.


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