BID Antibody (5C9): sc-56025
- BID Antibody (5C9) is a mouse monoclonal IgG1, cited in 40 publications, provided at 50 µg/0.5 ml
- raised against amino acids 61-118 of BID of human origin
- recommended for detection of BID of mouse, rat and human origin by WB and IP; also recommended for detection of bands at ~20, ~16 and ~14 kDa corresponding to the cleaved forms of Bid in apoptotic cells
- See BID (B-3): sc-373939 for BID antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BID Antibody (5C9). This work is in progress.
QUICK LINKS
SEE ALSO...
BID Antibody (5C9) is a mouse monoclonal IgG1 antibody that detects BID in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP) applications. BID, a crucial member of the Bcl-2 family, plays a significant role in the regulation of apoptosis, acting as a pro-apoptotic factor that can promote cell death in response to various cellular signals. BID′s importance lies in its ability to dimerize with anti-apoptotic proteins such as Bcl-2 and Bcl-x, thereby counteracting their protective effects and facilitating the apoptotic process. The presence of a BH3 domain in BID is essential for function, allowing interactions with these proteins and influencing the balance between cell survival and death. BID is predominantly localized in the cytosol but can also be found in membrane fractions, highlighting a dynamic role in cellular signaling pathways. BID is highly expressed in the kidney and is also detectable in other tissues such as the brain, spleen, liver, testis, and lung, underscoring relevance in various physiological and pathological contexts. anti-BID antibody (5C9) is an invaluable tool for researchers studying apoptosis and its implications in diseases such as cancer, where the regulation of cell death is often disrupted.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BID Antibody (5C9) | sc-56025 | 50 µg/0.5 ml | $316.00 |