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Laminin α-1 Antibody (H-300): sc-5582

 |  Datasheet

(Based on data analysis)

  • Laminin α-1 Antibody (H-300) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 1856-2099 of Laminin α-1 of human origin
  • recommended for detection of Laminin α-1 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
  • See 2 citations for Laminin α-1 Antibody (H-300)
 

See additional Laminin Antibodies including Laminin, Laminin alpha-1, Laminin beta-1, Laminin gamma-1, Laminin alpha-2, Laminin beta-2, Laminin gamma-2, Laminin alpha-3, Laminin beta-3, Laminin gamma-3, Laminin alpha-4, Laminin beta-4, Laminin alpha-5 and Laminin-5.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Laminin α-1 Antibody (H-300) sc-5582 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Laminin α-1 siRNA (h) sc-37125 10 µM $258
Laminin α-1 siRNA (m) sc-37126 10 µM $258
Laminin α-1 (h)-PR sc-37125-PR 10 µM, 20 µl $23
Laminin α-1 (m)-PR sc-37126-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Laminin α-1 shRNA Plasmid (h) sc-37125-SH 20 µg $520
Laminin α-1 shRNA Plasmid (m) sc-37126-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Laminin α-1 shRNA (h) Lentiviral Particles sc-37125-V 200 µl $625
Laminin α-1 shRNA (m) Lentiviral Particles sc-37126-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Caki-1 Cell Lysate sc-2224 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human LAMA1 284217 18p11.31 NM_005559 P25391
 150320
Mouse Lama1 16772 17 E1.1 P19137
 N/A
 

Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of laminins with stabilizing Type IV Collagen networks, Nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each laminin is a heterotrimer of a, b and y chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble and bind to other matrix macromolecules, and have unique and shared cell interactions mediated by integrins, dystroglycan and cognate laminin receptors. The human Laminin a-1 gene maps to chromosome 18p11.3 and is over-expressed in Alzheimer disease frontal cortex.

Laminin α-1 Antibody (H-300) Product Citations
See how others have used Laminin α-1 Antibody (H-300) and or Laminin α-1 Antibody (H-300) conjugates.


2 total citations
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Laminin α-1 Antibody (H-300) Data
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sc-5582
Laminin α-1 (H-300): sc-5582. Western blot analysis of Laminin α-1 expression in Caki-1 whole cell lysate.
sc-5582
Laminin α-1 (H-300): sc-5582. Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate cancer tissue showing membrane staining of tumor cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
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