epitope corresponding to amino acids 1-84 mapping at the N-terminus of Vimentin of human origin
recommended for detection of Vimentin of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine and porcine
Vimentin Background Information Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. Intermediate filaments are constructed from two-chain, a-helical, coiled-coil molecules arranged on an imperfect helical lattice and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. One such intermediate filament protein, Vimentin, is a general marker of cells originating in the mesenchyme. Vimentin is frequently coexpressed with other members of the intermediate filament family, such as the cytokeratins, in neoplasms including melanoma and breast carcinoma.
Vimentin (H-84) Product Citations
See how others have used Vimentin (H-84): sc-5565 antibody and or Vimentin (H-84) antibody conjugates.
28 total citations
Loading citations.
Vimentin (H-84)
Click on image to enlarge
Vimentin (H-84): sc-5565. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
Vimentin (H-84): sc-5565. Western blot analysis of Vimentin expression in HISM whole cell lysate. Note lower molecular weight Vimentin degradation products.
Vimentin (H-84): sc-5565. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoskeletal localization.