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home » Signaling Intermediates » eIF Antibody / eIF Antibodies » eIF2Bε (B-7): sc-55558

eIF2Bε (B-7) Antibody: sc-55558

  |  Datasheet
  • mouse monoclonal IgG1, 200µg/ml
  • raised against amino acids 422-711 mapping near the C-terminus of eIF2Bε of human origin
  • recommended for detection of eIF2Bε of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
 
Additional eIF Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human EIF2B5 8893 3q27.1 NM_003907 Q13144
 603945
Mouse Eif2b5 224045 16 A3 Q8CHW4
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
eIF2Bε (B-7) sc-55558 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
eIF2Bε siRNA (h) sc-35278 10 µM $258
eIF2Bε siRNA (m) sc-35279 10 µM $258
eIF2Bε (h)-PR sc-35278-PR 10 µM $23
eIF2Bεε (m)-PR sc-35279-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
eIF2Bε shRNA Plasmid (h) sc-35278-SH 20 µg $520
eIF2Bεε shRNA Plasmid (m) sc-35279-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
eIF2Bε shRNA (h) Lentiviral Particles sc-35278-V 200 µl $625
eIF2Bεε shRNA (m) Lentiviral Particles sc-35279-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
MOLT-4 Cell Lysate sc-2233 500 µg/200 µl $104
eIF2Bε (m): 293T Lysate sc-119973 100µg/200µl $205
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
eIF2Bε (h2): 293T Lysate sc-116495 100µg/200µl $205
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104

eIF2Bε Background Information
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF2B exists as a five subunit complex composed of eIF2Bå, eIF2Bß, eIF2B©, eIF2B∂, and eIF2Bé. The eIF2B complex catalyzes the exchange of GDP for GTP on the eIF2 complex, following the interaction of eIF2/GTP with the 40S ribosomal subunit. Guanine nucleotide exchange factor (GEF) activity is exhibited by the eIF2Bé subunit alone, but is greater in the presence of all five eIF2B subunits. Phosphorylation of eIF2 inhibits GEF activity of eIF2B, an inhibition that requires the eIF2Bå subunit.
eIF2Bε (B-7)
Click on image to enlarge
sc-55558
eIF2Bε (B-7): sc-55558. Western blot analysis of eIF2Bε expression in HeLa (A), NIH/3T3 (B) and KNRK (C) whole cell lysates.
sc-55558
eIF2Bε (B-7): sc-55558. Western blot analysis of eIF2Bε expression in non-transfected: sc-117752 (A) and human eIF2Bε transfected: sc-116495 (B) 293T whole cell lysates.
sc-55558
eIF2Bε (B-7): sc-55558. Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells (low and high magnification). Kindly provided by The Swedish Human Protein Atlas (HPA) program.
sc-55558
eIF2Bε (B-7): sc-55558. Western blot analysis of eIF2Bε expression in non-transfected 293T: sc-117752 (A), mouse eIF2Bε transfected 293T: sc-119973 (B) and KNRK (C) whole cell lysates.
sc-55558
eIF2Bε (B-7): sc-55558. Western blot analysis of eIF2Bε expression in non-transfected 293T: sc-117752 (A), mouse eIF2Bε transfected 293T: sc-119974 (B) and KNRK (C) whole cell lysates.
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