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QIP1 Antibody (P-15): sc-55270

 |  Datasheet

(Based on data analysis)
  • QIP1 Antibody (P-15) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of QIP1 of human origin
  • recommended for detection of QIP1 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-55270 P
 

See additional QIP Antibodies.

Ordering InformationGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
QIP1 Antibody (P-15) sc-55270 200 µg/ml $279
QIP1 (P-15) P sc-55270 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
QIP1 siRNA (h) sc-62916 10 µM $258
QIP1 siRNA (m) sc-62917 10 µM $258
QIP1 (h)-PR sc-62916-PR 10 µM, 20 µl $23
QIP1 (m)-PR sc-62917-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
QIP1 shRNA Plasmid (h) sc-62916-SH 20 µg $520
QIP1 shRNA Plasmid (m) sc-62917-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
QIP1 shRNA (h) Lentiviral Particles sc-62916-V 200 µl $625
QIP1 shRNA (m) Lentiviral Particles sc-62917-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
Ramos Cell Lysate sc-2216 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human KPNA4 3840 3q26.1 NM_002268 O00629
 602970
Mouse Kpna4 16649 3 E1 O35343
 N/A
 

QIP1, also known as KPNA4 (karyopherin å4), IPOA3 (importin å3) or SRP3, is a member of the importin å family. It is involved in nuclear import and forms a complex with the importin ∫ protein, karyopherin ∫1, functioning as its adapter protein. QIP1 binds to substrates containing nuclear localization signal (NLS) motifs, while karyopherin ∫1 facilitates the binding of the importin/substrate complex to the nuclear pore complex (NPC). Subsequently, the importin/substrate complex is translocated through the pore via a Ran-dependent mechanism. QIP1 contains one IBB domain at its hydrophilic N-terminus which is required for binding karyopherin ∫1 and ten ARM repeats in its hydrophobic central region. QIP1 is expressed at high levels in pancreas, lung, ovary, testis, small intestine, heart and skeletal muscle, exhibiting both cytoplasmic and nuclear localization.