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home » Transcription Regulators » MacroH2 Antibody / MacroH2 Antibodies » MacroH2A (H-20): sc-54843

MacroH2A (H-20) Antibody: sc-54843

  |  Datasheet
  • goat polyclonal IgG, 200µg/ml
  • epitope mapping within an internal region of MacroH2A of mouse origin
  • recommended for detection of MacroH2A of mouse and rat origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and avian
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-54843 X, 200 µg/0.1 ml
  • blocking peptide, sc-54843 P
 
Additional MacroH2 Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse H2afy2 404634 10 B4 Q8CCK0
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
MacroH2A (H-20) sc-54843 200 µg/ml $279
MacroH2A (H-20) P sc-54843 P
(peptide)
 100 µg/0.5 ml $61
MacroH2A (H-20) X sc-54843 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MacroH2A siRNA (m) sc-62576 10 µM $258
MacroH2A (m)-PR sc-62576-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MacroH2A shRNA Plasmid (m) sc-62576-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MacroH2A shRNA (m) Lentiviral Particles sc-62576-V 200 µl $625

MacroH2A Background Information
Eukaryotic histones are water soluble, basic nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer. The octamer consists of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. MacroH2A, also called core histone MacroH2A2 (mH2A2), is a variant Histone H2A, originally isolated in rat liver, that is nearly three times as large as conventional H2A. MacroH2A may be involved in stable X chromosome inactivation as it is enriched in inactive X chromosome chromatin.