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Cdc2 p34 Antibody (17): sc-54

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  • Cdc2 p34 Antibody (17) is a mouse monoclonal IgG2a (kappa light chain) provided at 200 µg/ml
  • raised against amino acids 224-230, mapping within a central region of Cdc2 of human origin
  • recommended for detection of Cdc2 p34 of multiple species (including, murine, human and Xenopus) by WB, IP, KA, IF and IHC(P)
  • agarose (sc-54 AC), 500 µg/0.25 ml agarose in 1 ml, for IP; HRP (sc-54 HRP), 200 µg/ml, for WB, IHC(P) and ELISA; phycoerythrin (sc-54 PE), fluorescein (sc-54 FITC), Alexa Fluor® 488 (sc-54 AF488) or Alexa Fluor® 647 (sc-54 AF647), 200 µg/ml, for IF, IHC(P) and FCM
  • TRITC (sc-54 TRITC, 200 µg/ml), for IF, IHC(P) and FCM.
  • See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP): sc-516102, m-IgGκ BP-FITC: sc-516140, m-IgGκ BP-PE: sc-516141, or m-IgGκ BP-B: sc-516142, our highly recommended recombinant alternatives to conventional secondary anti-mouse IgG reagents.
  • See 263 citations for Cdc2 p34 Antibody (17)
 

See additional Cdc Antibodies including Cdc, Cdc2, Cdc3, CdcA3, Cdc4, CdcA4, Cdc5, Cdc6, Cdc7, Cdc10, Cdc11, Cdc13, Cdc14, Cdc14 Phosphatase, Cdc15, Cdc16, Cdc20, Cdc23, Cdc24, Cdc25, Cdc26, Cdc27, Cdc28, Cdc34, Cdc35, Cdc37, Cdc40, Cdc42, Cdc45, Cdc50, Cdc50C, Cdc53 and Cdc123.

Also see chemical Cdc2 Inhibitors or chemical Cdc2 Substrates for functional analysis of cellular responses to Cdc2.


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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 Antibody (17) sc-54 200 µg/ml $279
Cdc2 p34 Antibody (17) AC sc-54 AC 500 µg/ml, 25% ag $366
Cdc2 p34 Antibody (17) Alexa Fluor® 488 sc-54 AF488 200 µg/ml $314
Cdc2 p34 Antibody (17) Alexa Fluor® 647 sc-54 AF647 200 µg/ml $314
Cdc2 p34 Antibody (17) FITC sc-54 FITC 200 µg/ml $292
Cdc2 p34 Antibody (17) HRP sc-54 HRP 200 µg/ml $279
Cdc2 p34 Antibody (17) PE sc-54 PE 200 µg/ml $303
Cdc2 p34 Antibody (17) TRITC sc-54 TRITC 200 µg/ml $282
 CRISPR KO, HDR and Nickase Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 CRISPR/Cas9 KO Plasmid (h) sc-400181 20 µg $345
Cdc2 p34 HDR Plasmid (h) sc-400181-HDR 20 µg $385
Cdc2 p34 Double Nickase Plasmid (h) sc-400181-NIC 20 µg $355
Cdc2 p34 Double Nickase Plasmid (h2) sc-400181-NIC-2 20 µg $355
Cdc2 p34 CRISPR/Cas9 KO Plasmid (m) sc-419582 20 µg $345
Cdc2 p34 CRISPR/Cas9 KO Plasmid (m2) sc-419582-KO-2 20 µg $345
Cdc2 p34 HDR Plasmid (m2) sc-419582-HDR-2 20 µg $385
Cdc2 p34 Double Nickase Plasmid (m) sc-419582-NIC 20 µg $355
Cdc2 p34 Double Nickase Plasmid (m2) sc-419582-NIC-2 20 µg $355
 CRISPR Activation Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 CRISPR Activation Plasmid (h) sc-400181-ACT 20 µg $345
Cdc2 p34 CRISPR Activation Plasmid (h2) sc-400181-ACT-2 20 µg $345
Cdc2 p34 Lentiviral Activation Particles (h) sc-400181-LAC 200 µl $395
Cdc2 p34 Lentiviral Activation Particles (h2) sc-400181-LAC-2 200 µl $395
Cdc2 p34 CRISPR Activation Plasmid (m) sc-419582-ACT 20 µg $345
Cdc2 p34 CRISPR Activation Plasmid (m2) sc-419582-ACT-2 20 µg $345
Cdc2 p34 Lentiviral Activation Particles (m) sc-419582-LAC 200 µl $395
Cdc2 p34 Lentiviral Activation Particles (m2) sc-419582-LAC-2 200 µl $395
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 siRNA (h) sc-29252 10 µM $258
Cdc2 p34 siRNA (m) sc-29253 10 µM $258
Cdc2 p34 (h)-PR sc-29252-PR 10 µM, 20 µl $23
Cdc2 p34 (m)-PR sc-29253-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 shRNA Plasmid (h) sc-29252-SH 20 µg $520
Cdc2 p34 shRNA Plasmid (m) sc-29253-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 shRNA (h) Lentiviral Particles sc-29252-V 200 µl $625
Cdc2 p34 shRNA (m) Lentiviral Particles sc-29253-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAMALWA Cell Lysate sc-2234 500 µg/200 µl $104
HeLa nuclear extract sc-2120 250 µ/0.05 ml $143
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
A-431 nuclear extract sc-2122 250 µ/0.05 ml $143
WEHI-231 Whole Cell Lysate sc-2213 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
HeLa + hydroxyurea Cell Lysate sc-24682 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CDC2 983 10q21.2 NM_001170406, NM_001170407, NM_001786, NM_033379 P06493
116940
Mouse Cdk1 12534 10 B5.3 NM_007659 P11440
N/A
 


In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.

Cdc2 p34 Antibody (17) Product Reviews

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Cdc2 p34 Antibody (17) Product Citations
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Cdc2 p34 Antibody (17) Data
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Cdc2 p34 (17): sc-54. Western blot analysis of Cdc2 p34 expression in non-transfected 293: sc-110760 (A), human Cdc2 p34 transfected 293: sc-128282 (B) and HeLa (C) whole cell lysates.
Cdc2 p34 (17): sc-54. Immunoperoxidase detection of Cdc2 p34 in formalin fixed, paraffin-embedded human testis tissue, showing nuclear staining of cells in seminiferous ducts. Detection reagent used: m-IgGκ BP-HRP: sc-516102.
Cdc2 p34 (17) HRP: sc-54 HRP. Direct western blot analysis of Cdc2 p34 expression in A-431 nuclear extract.
Cdc2 p34 (17): sc-54. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon carcinoma tissue showing nuclear staining of selected cells.
Cdc2 p34 (17): sc-54. Western blot analysis of Cdc2 p34 expression in untreated (A) and Licochalcone-A, Synthetic (sc-319884) treated (B) PC-3 whole cell lysates. Note down regulation of Cdc2 p34 expression in lane B.
Cdc2 p34 (17): sc-54. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing nuclear and cytoplasmic staining of cells in seminiferous ducts.
Cdc2 p34 (17): sc-54. Western blot analysis of Cdc2 p34 expression in HeLa whole cell lysate.
Cdc2 p34 (17): sc-54. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing nuclear and cytoplasmic staining of cells in germinal center.
Cdc2 p34 (17): sc-54. Western blot analysis of Cdc2 p34 expression in A-431 nuclear extract.
Cdc2 p34 (17): sc-54. Immunofluorescence staining of methanol-fixed HeLa cells showing specific staining of nuclei and centrosomes.
Cdc2 p34 (17): sc-54. Western blot analysis of Cdc2 p34 expression in non-transfected 293T: sc-117752 (A), mouse Cdc2 p34 transfected 293T: sc-119124 (B) and K-562 (C) whole cell lysates.
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