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CYP3A4 Antibody (HL3): sc-53850

 |  Datasheet

(Based on data analysis)

  • CYP3A4 Antibody (HL3) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against partially purified liver microsomes of human origin
  • recommended for detection of CYP3A4 of human origin by WB, IP and IF
  • See 4 citations for CYP3A4 Antibody (HL3)
 

See additional CYP Antibodies including CYP, CyP, Cyp21a1, CYP27C1, CYP2A12, CYP2A13, CYP2A22, CYP2A4, CYP2A5, CYP2A7, CYP2AB1, CYP2B10, CYP2B123, CYP2B13, CYP2B19, CYP2B9, Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c40, Cyp2c44, Cyp2c50, Cyp2c54, Cyp2c55, Cyp2c65, Cyp2c66, Cyp2c67, Cyp2c68, Cyp2c69, Cyp2c70, CYP2D10, CYP2D11, CYP2D12, CYP2D22, CYP2D26, CYP2D34, CYP2D40, CYP2D9, CYP2G1, CYP2J11, CYP2J12, CYP2J13, CYP2J5, CYP2J7, CYP2J8, CYP2J9, CYP2T4, Cyp3a11, Cyp3a13, Cyp3a16, Cyp3a25, Cyp3a41a, Cyp3a41b, CYP3A43, Cyp3a44, Cyp3a57, Cyp3a59, CYP4A12A, CYP4A12B, CYP4A29, CYP4A30B, CYP4F12, Cyp4f13, Cyp4f14, Cyp4f15, Cyp4f16, Cyp4f17, CYP4F22, CYP4F3, Cyp4f37, Cyp4f39, Cyp4f40, CYP4F43P, CYP4F8, CYP4V3, CYP51A1, CYP2A, CYP3A, CYP4A, CYP11B, CYP1A1, CYP1B1, CYP1A2, CYP19, CYP2B1, CYP2E1, CYP2F1, CYP2R1, CYP2S1, CYP2U1, CYP2W1, CYP2B2, CYP2F2, CYP2J2, CYP24, CYP26A1, CYP2A6, CYP2B6, CYP2C6, CYP2D6, CYP2J6, CYP2C8, CYP2C9, CYP3A1, CYP3A4, CYP3A5, CYP3A7, CYP4A1, CYP4B1, CYP4X1, CYP4Z1, CYP4A2, CYP4F2, CYP4V2, CYP4A3, CYP46, CYP7A1, CYP7B1, CYP8B1, CYP11A1, CYP11B1, CYP17A1, CYP20A1, CYP21A2, CYP2C18, CYP2C19, CYP27A1, CYP27B1, CYP39A1, CYP4A10, CYP4A11, CYP4F11, CYP4A14, CYP4A22, CYP4A31 and CYP4A32.

Also see CYP3A4 Inhibitors or CYP3A4 Substrates for functional analysis of cellular responses to CYP3A4.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
CYP3A4 Antibody (HL3) sc-53850 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CYP3A4 siRNA (h) sc-43711 10 µM $258
CYP3A4 (h)-PR sc-43711-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CYP3A4 shRNA Plasmid (h) sc-43711-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CYP3A4 shRNA (h) Lentiviral Particles sc-43711-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CYP3A4 1576 7q22.1 NM_017460 P08684
 124010
 

Cytochrome P450 3A (CYP3A) genes encode monooxygenases—enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A, the most abundant p450 enzyme in human liver, is responsible for the metabolism of more than 50% of all clinical drugs. CYP3A family members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster maps to gene locus 7q21.3-q22.1 and consists of four genes (CYP3A4, CYP3A5, CYP3A7 andCYP3A43) and two pseudogenes (CYP3A5P1 and CYP3A5P2). CYP3A4 is abundant in the endoplasmic reticulum of liver cells and upper intestinal enterocytes. CYP3A4 expression is inducible by glucocorticoids pharmacological agents.

CYP3A4 Antibody (HL3) Product Citations
See how others have used CYP3A4 Antibody (HL3) and or CYP3A4 Antibody (HL3) conjugates.


4 total citations
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CYP3A4 Antibody (HL3) Data
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sc-53850
CYP3A4 (HL3): sc-53850. Western blot analysis of CYP3A4 expression in human liver tissue extract.
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