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- goat polyclonal IgG, 200 µg/ml
- epitope mapping within an internal region of MAP-2 of human origin
- recommended for detection of MAP-2A, MAP-2B, MAP-2C and MAP-2D of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- blocking peptide, sc-5359 P
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Ordering InformationProduct Citations
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MAP-2 Background Information Microtubules, the primary component of the cytoskeletal network, interact with proteins called microtubule-associated proteins (MAPs). The microtubule-associated proteins can be divided into two groups, structural and dynamic. The structural microtubule-associated proteins, MAP-1A, MAP-1B, MAP-2A, MAP-2B and MAP-2C, stimulate tubulin assembly, enhance micro-tubule stability and influence the spatial distribution of microtubules within cells. Both MAP-1 and, to a greater extent, MAP-2 have been implicated as agents of microtubule depolymerization by suppressing the dynamic instability of the microtubules. The suppression of microtubule dynamic instability by the MAP proteins is thought to be associated with phosphorylation of the MAPs.
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See how others have used MAP-2 (D-19): sc-5359 antibody and or MAP-2 (D-19) antibody conjugates.
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MAP-2 (D-19)
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MAP-2 (D-19): sc-5359. Western blot analysis of MAP-2 expression in non-transfected: sc-117752 (A) and truncated mouse MAP-2 transfected: sc-121505 (B) 293T whole cell lysates.
MAP-2 (D-19): sc-5359. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoskeleton localization.
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