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TSHR Antibody (3B12): sc-53542

 |  Datasheet

(Based on data analysis)

  • TSHR Antibody (3B12) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • rased against amino acids 1-415 of TSHR of human origin
  • recommended for detection of TSHR of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM; also reactive with additional species, including bovine, porcine, feline and canine
  • fluorescein (sc-53542 FITC) and phycoerythrin (sc-53542 PE) conjugates for FCM, 100 tests
  • See 2 citations for TSHR Antibody (3B12)
 

See additional TSHR Antibodies.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IHC(P)   FCM   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
TSHR Antibody (3B12) sc-53542 200 µg/ml $279
TSHR Antibody (3B12) FITC sc-53542 FITC 100 tests in 2 ml $292
TSHR Antibody (3B12) PE sc-53542 PE 100 tests in 2 ml $303
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TSHR CRISPR/Cas9 KO Plasmid (h) sc-400848 20 µg $345
TSHR HDR Plasmid (h) sc-400848-HDR 20 µg $385
TSHR CRISPR/Cas9 KO Plasmid (m) sc-423527 20 µg $345
TSHR HDR Plasmid (m) sc-423527-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TSHR siRNA (h) sc-36754 10 µM $258
TSHR siRNA (m) sc-36755 10 µM $258
TSHR (h)-PR sc-36754-PR 10 µM, 20 µl $23
TSHR (m)-PR sc-36755-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TSHR shRNA Plasmid (h) sc-36754-SH 20 µg $520
TSHR shRNA Plasmid (m) sc-36755-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TSHR shRNA (h) Lentiviral Particles sc-36754-V 200 µl $625
TSHR shRNA (m) Lentiviral Particles sc-36755-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
IMR-32 Cell Lysate sc-2409 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TSHR 7253 14q31.1 NM_000369, NM_001018036 P16473
609152
Mouse Tshr 22095 12 D3 P47750
N/A
 


Various hormones are secreted from the anterior pituitary during development and growth, including thyroid-stimulating hormone (TSH, also known as thyrotropin), follicle-stimulating hormone (FSH) and leutinizing hormone (LH). TSH, FSH, and LH are heterodimers formed from a common alpha chain and a unique beta chain. TSH is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Graves disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.

TSHR Antibody (3B12) Product Citations
See how others have used TSHR Antibody (3B12) and or TSHR Antibody (3B12) conjugates.


2 total citations
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TSHR Antibody (3B12) Data
Click on image to enlarge
TSHR (3B12): sc-53542. Immunoperoxidase staining of formalin fixed, paraffin-embedded human thyroid gland tissue showing cytoplasmic staining of glandular cells.
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