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CD8-α Antibody (KT15): sc-53473

 |  Datasheet

(Based on data analysis)
  • CD8-α Antibody (KT15) is a rat monoclonal IgG2a provided at 200 µg/ml
  • raised against T cell clone C6 of mouse origin
  • recommended for detection of CD8-α chain of mouse origin by IF and FCM
  • fluorescein (sc-53473 FITC) and phycoerythrin (sc-53473 PE) conjugates for FCM, 100 tests
 

See additional CD8 Antibodies including CD8, CD8-alpha and CD8-beta.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
IF   FCM   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
CD8-α Antibody (KT15) sc-53473 200 µg/ml $279
CD8-α Antibody (KT15) FITC sc-53473 FITC 100 tests in 2 ml $292
CD8-α Antibody (KT15) PE sc-53473 PE 100 tests in 2 ml $303
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CD8-α siRNA (m) sc-43677 10 µM $258
CD8-α (m)-PR sc-43677-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CD8-α shRNA Plasmid (m) sc-43677-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CD8-α shRNA (m) Lentiviral Particles sc-43677-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Cd8a 12525 6 C1 P01731
 N/A
 

The T cell receptor (TCR) is a heterodimer composed of either å and ∫ or © and ∂ chains. CD3 chains and the CD4 or CD8 (CD8-å and CD8-∫) co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8 proteins; T helper cells express CD4 proteins and T cytotoxic cells display CD8 proteins. CD8s are cell surface glycoproteins that exist as two chain complex (åå or å∫) receptors that bind class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 proteins is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.