PIP2 Background Information Phosphatidylinositol 4,5-biphosphate (PIP2) is a low-abundance membrane phospholipid that functions in a variety of cellular processes, such as membrane trafficking, plasma membrane-cytoskeleton linkages, synaptic vesicle recycling, second messenger signaling, cell adhesion and motility and regulation of proteins involved in phospholipid metabolism. It also stimulates the Ca2+-activated ATPase, implicating that changes in the cellular concentration of PIP2 may be important in regulating Ca2+ transport by the endoplasmic reticulum. PIP2 and intracellular Ca2+ regulate the taste transduction ion channel TRPM5. PIP2 serves as an effector of multiple downstream proteins and its levels are regulated by hormones. It may also serve as a second messenger in the control of cytoskeleton-membrane adhesion.
PIP2 (PIP2 2C11) Product Citations
See how others have used PIP2 (PIP2 2C11): sc-53412 antibody and or PIP2 (PIP2 2C11) antibody conjugates.
