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PCTAIRE-1 (G6.1) Antibody: sc-53410 |
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- mouse monoclonal IgG2b, 200µg/ml
- raised against amino acids 2-19 of PCTAIRE-1 of human origin
- recommended for detection of PCTAIRE-1 of mouse, rat, human and Xenopus origin by WB, IP, IF and IHC(P)
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PCTAIRE-1 Background Information Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with cyclins to phosphorylate key substrates involved in cell cycle progression. Another family of proteins, Cdk inhibitors, also play a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Members of the Cdk family include Cdk2–Cdk8, PCTAIRE-1–3, PITALRE and PITSLRE. PCTAIRE-1, PCTAIRE-2 and PCTAIRE-3 comprise a subfamily of cdc2-related serine/threonine kinases. PCTAIRE-1, which is expressed primarily in mammalian brain, interacts with a variety of proteins, and is thought to be part of a multiple signal transduction cascade. PCTAIRE-2, also with expression in brain, may be important in terminally differentiated neurons. The human PCTAIRE-3 gene maps to chromosome 1q31-q32. |
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PCTAIRE-1 (G6.1)
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PCTAIRE-1 (G6.1): sc-53410. Western blot analysis of PCTAIRE-1 expression in mouse kidney (A) tissue extract and NIH/3T3 (B), U-87 MG (C), A549 (D) and MCF7 (E) whole cell lysates.
PCTAIRE-1 (G6.1): sc-53410. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pnacreas tissue showing cytoplasmic staining of exocrine glandular cells and islet cells (low and high magnification). Kindly provided by The Swedish Human Protein Atlas (HPA) program.
PCTAIRE-1 (G6.1): sc-53410. Western blot analysis of PCTAIRE-1 expression in non-transfected: sc-117752 (A) and mouse PCTAIRE-1 transfected: sc-122442 (B) 293T whole cell lysates.
PCTAIRE-1 (G6.1): sc-53410. Western blot analysis of PCTAIRE-1 expression in non-transfected: sc-117752 (A) and mouse PCTAIRE-1 transfected: sc-122443 (B) 293T whole cell lysates.
PCTAIRE-1 (G6.1): sc-53410. Western blot analysis of PCTAIRE-1 expression in non-transfected 293T: sc-117752 (A), human PCTAIRE-1 transfected 293T: sc-158821 (B) and U-87 MG (C) whole cell lysates.
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