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PCTAIRE-1 (G6.1) Antibody: sc-53410

 |  Datasheet
  • mouse monoclonal IgG2b, 200µg/ml
  • raised against amino acids 2-19 of PCTAIRE-1 of human origin
  • recommended for detection of PCTAIRE-1 of mouse, rat, human and Xenopus origin by WB, IP, IF and IHC(P)
 
Additional PCTAIRE Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PCTK1 5127 Xp11.3 NM_006201, NM_033018 Q00536
311550
Mouse Pctk1 18555 X A1.3 Q04735
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
PCTAIRE-1 (G6.1) sc-53410 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PCTAIRE-1 siRNA (h) sc-37584 10 µM $258
PCTAIRE-1 siRNA (m) sc-37585 10 µM $258
PCTAIRE-1 (h)-PR sc-37584-PR 10 µM $23
PCTAIRE-1 (m)-PR sc-37585-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PCTAIRE-1 shRNA Plasmid (h) sc-37584-SH 20 µg $520
PCTAIRE-1 shRNA Plasmid (m) sc-37585-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PCTAIRE-1 shRNA (h) Lentiviral Particles sc-37584-V 200 µl $625
PCTAIRE-1 shRNA (m) Lentiviral Particles sc-37585-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PCTAIRE-1 (m2): 293T Lysate sc-122443 100µg/200µl $205
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
U-87 MG Cell Lysate sc-2411 500 µg/200 µl $104
mouse kidney extract sc-2255 500 µg/200 µl $104
A549 Cell Lysate sc-2413 500 µg/200 µl $104

PCTAIRE-1 Background Information
Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with cyclins to phosphorylate key substrates involved in cell cycle progression. Another family of proteins, Cdk inhibitors, also play a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Members of the Cdk family include Cdk2–Cdk8, PCTAIRE-1–3, PITALRE and PITSLRE. PCTAIRE-1, PCTAIRE-2 and PCTAIRE-3 comprise a subfamily of cdc2-related serine/threonine kinases. PCTAIRE-1, which is expressed primarily in mammalian brain, interacts with a variety of proteins, and is thought to be part of a multiple signal transduction cascade. PCTAIRE-2, also with expression in brain, may be important in terminally differentiated neurons. The human PCTAIRE-3 gene maps to chromosome 1q31-q32.

PCTAIRE-1 (G6.1)
Click on image to enlarge
PCTAIRE-1 (G6.1): sc-53410. Western blot analysis of PCTAIRE-1 expression in mouse kidney (A) tissue extract and NIH/3T3 (B), U-87 MG (C), A549 (D) and MCF7 (E) whole cell lysates.
PCTAIRE-1 (G6.1): sc-53410. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pnacreas tissue showing cytoplasmic staining of exocrine glandular cells and islet cells (low and high magnification). Kindly provided by The Swedish Human Protein Atlas (HPA) program.
PCTAIRE-1 (G6.1): sc-53410. Western blot analysis of PCTAIRE-1 expression in non-transfected: sc-117752 (A) and mouse PCTAIRE-1 transfected: sc-122442 (B) 293T whole cell lysates.
PCTAIRE-1 (G6.1): sc-53410. Western blot analysis of PCTAIRE-1 expression in non-transfected: sc-117752 (A) and mouse PCTAIRE-1 transfected: sc-122443 (B) 293T whole cell lysates.
PCTAIRE-1 (G6.1): sc-53410. Western blot analysis of PCTAIRE-1 expression in non-transfected 293T: sc-117752 (A), human PCTAIRE-1 transfected 293T: sc-158821 (B) and U-87 MG (C) whole cell lysates.
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