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TTF-1 (8G7G3/1) Antibody: sc-53136

 |  Datasheet
  • mouse monoclonal IgG1, 200µg/ml
  • raised against full length recombinant TTF-1 of rat origin
  • recommended for detection of TTF-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
 
Additional TTF Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human NKX2-1 7080 14q13.3 NM_003317 P43699
610978
Mouse Nkx2-1 21869 12 C1 P50220
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
TTF-1 (8G7G3/1) sc-53136 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TTF-1 siRNA (h) sc-36756 10 µM $258
TTF-1 siRNA (m) sc-36757 10 µM $258
TTF-1 (h)-PR sc-36756-PR 10 µM $23
TTF-1 (m)-PR sc-36757-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TTF-1 shRNA Plasmid (h) sc-36756-SH 20 µg $520
TTF-1 shRNA Plasmid (m) sc-36757-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TTF-1 shRNA (h) Lentiviral Particles sc-36756-V 200 µl $625
TTF-1 shRNA (m) Lentiviral Particles sc-36757-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
A549 Cell Lysate sc-2413 500 µg/200 µl $104
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
TTF-1 (h2): 293T Lysate sc-159187 100µg/200µl $205

TTF-1 Background Information
TTF-1 (thyroid transcription factor-1, BCH, BHC, NK-2, Nkx2.1, Nkx2A, TEBP, TTF1) is a member of the Nkx2 family of homeodomain-containing transcription factors and regulates the transcriptional activity of thyroid-specific genes. TTF-1 influences organogenisis and the maintenance of the differentiated phenotypes of various tissues including thyroid, lung and brain. TTF-1, which is present in the epithelium of the lung, regulates transcription of the surfactant proteins (SP) A, B and C and is essential for lung morphogenesis. In the thyroid, TTF-1 elevates the expression of thyroid specific markers, thyroglobulin, thyroperoxidase and thyrotropin receptors. TTF-1 interacts with SRC-1 and CBP in vitro.

TTF-1 (8G7G3/1)
Click on image to enlarge
TTF-1 (8G7G3/1): sc-53136. Western blot analysis of TTF-1 expression in TT whole cell lysate.
TTF-1 (8G7G3/1): sc-53136. Western blot analysis of TTF-1 expression in non-transfected: sc-117752 (A) and human TTF-1 transfected: sc-159187 (B) 293T whole cell lysates.
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