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- rat monoclonal IgM, 200µg/ml
- raised against RAW264.7 mouse cell line
- recommended for detection of CD53 of mouse origin by FCM
- fluorescein (sc-53057 FITC) and phycoerythrin (sc-53057 PE) conjugates for FCM, 100 tests
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Ordering Information
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Mouse |
Cd53 |
12508 |
3 F2.3 |
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Q61451
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N/A |
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CD53 Background Information
The CD53 antigen is a member of the tetraspanin membrane protein family that is expressed in the lymphoid-myeloid lineage. The tetraspanin superfamily (CD9, CD37, CD53, CD63, CD81 and CD82) comprises a group of cell-surface proteins that are involved in cell activation and signal transduction as well as in cell adhesion, motility and metastasis. Tetraspanin transmembrane proteins have a metastasis suppressor effect by acting as cell motility brakes in tumor cells. Human neutrophils express high levels of CD53, an N-glycosylated pan-leukocyte antigen and the true homolog of the rat MRC-OX-44 antigen. CD53 is expressed on B cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T cells. |
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CD53 (OX80)
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CD53 (OX80): sc-53057. Indirect FCM analysis of mouse peripheral blood leukocytes stained with CD53 (OX80), followed by FITC-conjugated goat anti-rat IgM. Black line histogram represents the isotype control, normal rat IgM: sc-3885. |
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