santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » Cell Cycle Proteins » Cdc Antibody / Cdc Antibodies » Cdc2 p34 (PSTAIRE): sc-53

Cdc2 p34 (PSTAIRE) Antibody: sc-53

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope mapping within the conserved PSTAIRE domain of Cdc2 p34 of human origin
  • recommended for detection of Cdc2 p34 and other cyclin dependent kinases containing PSTAIRE or PFTAIRE motifs of mouse, rat, human, chicken, yeast, Drosophila and Xenopus origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-53 P
 
Additional Cdc Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CDC2 983 10q21.2 NM_001786, NM_033379 P06493
 116940
Human CDK2 1017 12q13.2 NM_001798, NM_052827 P24941
 116953
Human CDK3 1018 17q25.1 NM_001258 Q00526
 123828
Human ALS2CR7 65061 2q33.1 NM_139158 Q96Q40
 n/a
Mouse Cdc2a 12534 10 B5.3 P11440
 N/A
Mouse Cdk2 12566 10 D3 P97377
 N/A
Mouse 69681
N/A
Mouse Pftk2 271697 1 C1.3 Q3V3A1
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 (PSTAIRE) sc-53 200 µg/ml $279
Cdc2 p34 (PSTAIRE) P sc-53 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 siRNA (h) sc-29252 10 µM $258
Cdc2 p34 siRNA (m) sc-29253 10 µM $258
Cdc2 p34 (h)-PR sc-29252-PR 10 µM $23
Cdc2 p34 (m)-PR sc-29253-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 shRNA Plasmid (h) sc-29252-SH 20 µg $520
Cdc2 p34 shRNA Plasmid (m) sc-29253-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc2 p34 shRNA (h) Lentiviral Particles sc-29252-V 200 µl $625
Cdc2 p34 shRNA (m) Lentiviral Particles sc-29253-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAMALWA Cell Lysate sc-2234 500 µg/200 µl $104
HeLa nuclear extract sc-2120 1000 µg $143
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
A-431 nuclear extract sc-2122 1000 µg $143
WEHI-231 Whole Cell Lysate sc-2213 500 µg/200 µl $104
Cdk2 (m): 293T Lysate sc-119146 100µg/200µl $205
Cdk2 (h2): 293T Lysate sc-172351 100µg/200µl $205
HeLa + hydroxyurea Cell Lysate sc-24682 500 µg/200 µl $104

Cdc2 p34 Background Information
In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.

Cdc2 p34 (PSTAIRE) Product Citations
See how others have used Cdc2 p34 (PSTAIRE): sc-53 antibody and or Cdc2 p34 (PSTAIRE) antibody conjugates.


78 total citations
Loading citations.
 
Cdc2 p34 (PSTAIRE)
Click on image to enlarge
sc-53
Cdc2 p34 (PSTAIRE): sc-53. Western blot analysis of Cdc2 p34 expression in HeLa nuclear extract (A) and MCF7 whole cell lysate (B).
sc-53
Cdc2 p34 (PSTAIRE): sc-53. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
sc-53
Cdc2 p34 (PSTAIRE): sc-53. Western blot analysis of Cdc2 p34 expression in non-transfected 293: sc-110760 (A), human Cdc2 p34 transfected 293: sc-128282 (B) and HeLa (C) whole cell lysates.
sc-53
Cdc2 p34 (PSTAIRE): sc-53. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and mouse Cdk2 transfected: sc-119146 (B) 293T whole cell lysates.
sc-53
Cdc2 p34 (PSTAIRE): sc-53. Western blot analysis of Cdc2 p34 expression in non-transfected 293T: sc-117752 (A), mouse Cdc2 p34 transfected 293T: sc-119124 (B) and K-562 (C) whole cell lysates.
sc-53
Cdc2 p34 (PSTAIRE): sc-53. Western blot analysis of Cdk2 expression in non-transfected 293T: sc-117752 (A), human Cdk2 transfected 293T: sc-172351 (B) and NAMALWA (C) whole cell lysates.
sc-53
Western blot analysis of Cdc2 p34 phosphorylation in untreated (A,F), Hydroxyurea treated (B,G), nocodazole treated (C,H), Hydroxyurea and lambda protein phosphatase treated (D,I) and nocodazole and lambda protein phosphatase treated (E,J) HeLa whole cell lysates. Antibodies tested include p-Cdc2 p34 (Tyr 15)-R: sc-7989-R (A-E) and p-Cdc2 p34 (PSTAIRE): sc-53 (F-J).
sc-53
Western blot analysis of Cdc2 p34 phosphorylation in untreated (A,D), nocodazole treated (B,E) and nocodazole and lambda protein phosphatase treated (C,F) HeLa whole cell lysates. Antibodies tested include p-Cdc2 p34 (Thr 161)-R: sc-12341-R (A,B,C) and p-Cdc2 p34 (PSTAIRE): sc-53 (D,E,F).
sc-53
Cdc2 p34 (PSTAIRE): sc-53. Western blot analysis of ALS2CR7 expression in non-transfected 293: sc-110760 (A), human ALS2CR7 transfected 293: sc-176819 (B) and HeLa (C) whole cell lysates.
sc-53
Cdc2 p34 (PSTAIRE): sc-53. Western blot analysis of Cdc2 p34 expression in A-431 whole cell lysate.
sc-53
Cdc2 p34 (PSTAIRE): sc-53. Western blot analysis of Cdc2 p34 expression in untreated (A) and Licochalcone-A, Synthetic (sc-319884) treated (B) PC-3 whole cell lysates. Note down regulation of Cdc2 p34 expression in lane B.
Download
Datasheets
Get Adobe Acrobat Reader