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p-AR Antibody (156C135.2): sc-52894

 |  Datasheet

(Based on data analysis)
  • p-AR Antibody (156C135.2) is a mouse monoclonal IgG provided at 100 µg/ml
  • raised against a synthetic peptide corresponding to amino acids 207-221 of human origin, containing the serine 213 phosphorylation site
  • recommended for detection of Ser 213 and Ser 210 phosphorylated Androgen Receptor of mouse, rat and human origin by WB; also reactive with additional species, including porcine and canine
  • See 2 citations for p-AR Antibody (156C135.2)
 

See additional Androgen Receptor Antibodies.

Also see Androgen Receptor Inhibitors for functional analysis of cellular responses to Androgen Receptor.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-AR Antibody (156C135.2) sc-52894 100 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AR siRNA (h) sc-29204 10 µM $258
AR siRNA (m) sc-29203 10 µM $258
AR (h)-PR sc-29204-PR 10 µM, 20 µl $23
AR (m)-PR sc-29203-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AR shRNA Plasmid (h) sc-29204-SH 20 µg $520
AR shRNA Plasmid (m) sc-29203-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AR shRNA (h) Lentiviral Particles sc-29204-V 200 µl $625
AR shRNA (m) Lentiviral Particles sc-29203-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human AR 367 Xq12 NM_000044, NM_001011645 P10275
 313700
Mouse Ar 11835 X C3 P19091
 N/A
 

Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about three times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least six-fold increase in androgen receptor stability. Akt phosphorylates human AR at Serines 210 and 790. The synthetic androgen R1881 elevates phosphorylation of Serines 308 and 650 in vitro .

p-AR Antibody (156C135.2) Product Citations
See how others have used p-AR Antibody (156C135.2) and or p-AR Antibody (156C135.2) conjugates.


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