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home » Homeodomain Proteins » Octamer-Binding Protein Antibody / Octamer-Binding Protein Antibodies » Oct-3/4 (C-10): sc-5279

Oct-3/4 (C-10) Antibody: sc-5279

  |  Datasheet
  • mouse monoclonal IgG2b; 200 µg/ml
  • raised against amino acids 1-134 of Oct-3/4 of human origin
  • recommended for detection of Oct-3/4 of mouse, rat and human origin by WB, IP, IF, IHC(P), ELISA and indirect FCM using PE-conjugated goat anti-mouse IgG: sc-3738; non cross-reactive with Oct-3/4 isoform B
  • agarose conjugate for IP studies, sc-5279 AC, 500 µg/0.25 ml agarose
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-5279 X, 200 µg/0.1 ml
 
Additional Octamer-Binding Protein Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   FCM   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human POU5F1 5460 6p21.33 NM_002701, NM_203289 Q01860
 164177
Mouse Pou5f1 18999 17 B1 P20263
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Oct-3/4 (C-10) sc-5279 200 µg/ml $279
Oct-3/4 (C-10) AC sc-5279 AC 500µg/ml, 25%ag $366
Oct-3/4 (C-10) X sc-5279 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Oct-3/4 siRNA (h) sc-36123 10 µM $258
Oct-3/4 siRNA (m) sc-36124 10 µM $258
Oct-3/4 siRNA (h2) sc-43980 10 µM $258
Oct-3/4 (h)-PR sc-36123-PR 10 µM $23
Oct-3/4 (m)-PR sc-36124-PR 10 µM $23
Oct-3/4 (h)-PR sc-43980-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Oct-3/4 shRNA Plasmid (h) sc-36123-SH 20 µg $520
Oct-3/4 shRNA Plasmid (m) sc-36124-SH 20 µg $520
Oct-3/4 shRNA Plasmid (h) sc-43980-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Oct-3/4 shRNA (h) Lentiviral Particles sc-36123-V 200 µl $625
Oct-3/4 shRNA (m) Lentiviral Particles sc-36124-V 200 µl $625
Oct-3/4 shRNA (h) Lentiviral Particles sc-43980-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
F9 Cell Lysate sc-2245 500 µg/200 µl $104
mouse kidney extract sc-2255 500 µg/200 µl $104

Oct-3/4 Background Information
POU5F1 (POU domain, class 5, transcription factor 1), also known as octamer-binding transcription factor-3 (Oct-3, Otf-3), octamer-binding transcription factor-4 (Oct-4, Otf-4) and Oct-3/4, modulates embryonic stem (ES) cell populations by influencing lineage commitment. Oct-3/4 sustains stem-cell self-renewal and differentiation pathways. Transcription factors containing the POU homeodomain regulate tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. Oct-3/4 is capable of inducing rapid proliferation and tumorigenic properties of ES cells through activation of the UTF1 gene. In humans, two Oct-3/4 isoforms contribute to influencing the undifferentiated phenotype of ES cells. Oct-3/4 pseudogenes localizing to human chromosomes 10 and 8 are reported to be transcribed in certain cancer cell lines and tissues.

Oct-3/4 (C-10) Product Citations
See how others have used Oct-3/4 (C-10): sc-5279 antibody and or Oct-3/4 (C-10) antibody conjugates.


110 total citations
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Oct-3/4 (C-10)
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sc-5279
Oct-3/4 (C-10): sc-5279. Indirect, intracellular FCM analysis of fixed and permeabilized F9 cells stained with Oct-3/4 (C-10), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG2b: sc-3879.
sc-5279
Oct-3/4 (C-10): sc-5279. Immunofluorescence staining of paraformaldehyde fixed multicell mouse embryo showing nuclear localization. Kindly provided by Dr. Kira Foygel, Stanford University.
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