IL-1RII Antibody (6G5): sc-52678
- IL-1RII Antibody (6G5) is a mouse monoclonal IgG2a, cited in 2 publications, provided at 100 µg/ml
- raised against IL-1RII of human origin
- recommended for detection of IL-1RII of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IL-1RII Antibody (6G5). This work is in progress.
IL-1RII Antibody (6G5) is a mouse monoclonal IgG2a antibody that detects interleukin-1 receptor type II (IL-1RII) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). IL-1RII plays a crucial role in regulating inflammatory responses by acting as a decoy receptor for pro-inflammatory cytokine interleukin-1 (IL-1), preventing activation of signaling pathways that would otherwise lead to inflammation. This decoy mechanism helps maintain immune homeostasis by sequestering IL-1 from signaling receptors, mitigating excessive inflammatory responses that can lead to tissue damage and chronic inflammatory diseases. The soluble form of IL-1R accessory protein significantly enhances IL-1α and IL-1β binding affinity to IL-1RII, highlighting complex regulatory mechanisms involved in IL-1-mediated inflammation. Anti-IL-1RII antibody (6G5) enables researchers to explore the balance of pro-inflammatory and anti-inflammatory signals, advancing understanding of immune regulation and potential therapeutic targets for inflammatory conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-1RII Antibody (6G5) | sc-52678 | 100 µg/ml | $322.00 |