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CD14 Antibody (61D3): sc-52457

 |  Datasheet

(Based on data analysis)

  • CD14 Antibody (61D3) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • recommended for detection of human CD14 of human origin by IP, IF and FCM
  • fluorescein (sc-52457 FITC), phycoerythrin (sc-52457 PE), PerCP (sc-52457 PerCP) and PerCP-Cy5.5 (sc-52457 PCPC5) conjugates for FCM, 100 tests
  • Alexa Fluor® 488 (sc-52457 AF488) and Alexa Fluor® 647 (sc-52457 AF647) conjugates for FCM or immunofluorescence; 100 µg/2 ml
 

See additional CD14 Antibodies.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CD14 Antibody (61D3) sc-52457 200 µg/ml $279
CD14 Antibody (61D3) Alexa Fluor® 488 sc-52457 AF488 100 µg/2 ml $314
CD14 Antibody (61D3) Alexa Fluor® 647 sc-52457 AF647 100 µg/2 ml $314
CD14 Antibody (61D3) FITC sc-52457 FITC 100 tests in 2 ml $292
CD14 Antibody (61D3) PCPC5 sc-52457 PCPC5 100 tests in 2 ml $310
CD14 Antibody (61D3) PE sc-52457 PE 100 tests in 2 ml $303
CD14 Antibody (61D3) PerCP sc-52457 PerCP 100 tests in 2 ml $310
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CD14 CRISPR/Cas9 KO Plasmid (h) sc-400344 20 µg $345
CD14 HDR Plasmid (h) sc-400344-HDR 20 µg $385
CD14 CRISPR/Cas9 KO Plasmid (m) sc-419531 20 µg $345
CD14 HDR Plasmid (m) sc-419531-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CD14 siRNA (h) sc-29248 10 µM $258
CD14 (h)-PR sc-29248-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CD14 shRNA Plasmid (h) sc-29248-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CD14 shRNA (h) Lentiviral Particles sc-29248-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CD14 929 5q31.3 NM_000591, NM_001040021 P08571
158120
 


Lipopolysaccharide (LPS) elicits the secretion of mediators and cytokines produced by activated macrophages and monocytes. CD14 is a glycosylphosphatidylinositol (GPI)-anchored protein found on the surfaces of monocytes and polymorphonuclear leukocytes. CD14 functions as a receptor for LPS, resulting in the secretion of various proteins. An important component in the LPS activation of monocytes through the CD14 receptor is the “adapter molecule,” lipopolysaccharide binding protein (LBP). There are two forms of CD14, a membrane-associated form (mCD14), and a soluble form (sCD14). mCD14 responds to LPS alone and facilitates the secretion of proteins, while cells not expressing mCD14 fail to respond to LPS. The cells that lack mCD14 respond to LPS/LBP in the presence of sCD14 (7).

CD14 Antibody (61D3) Data
Click on image to enlarge
CD14 (61D3): sc-52457. Indirect FCM analysis of human peripheral blood leukocytes stained with CD14 (61D3), followed by PE-conjugated goat anti-mouse IgG1: sc-3764. Black line histogram represents the isotype control, normal mouse IgG1: sc-3877.
CD14 (61D3) AF647: sc-52457 AF647. FCM analysis of THP-1 cells. Black line histogram represents the isotype control, normal mouse IgG1: sc-24636.
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