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MEK-2 Antibody (N-20): sc-524

 |  Datasheet

(Based on data analysis)

  • MEK-2 Antibody (N-20) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the N-terminus of MEK-2 of human origin
  • recommended for detection of MEK-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
  • blocking peptide, sc-524 P
  • agarose conjugate for IP studies, sc-524 AC, 500 µg/0.25 ml agarose
  • See 21 citations for MEK-2 Antibody (N-20)
 

See additional MEK Antibodies including MEK, MEK, MEK-1, MEK-2, MEK-3, MEK-4, MEK-5, MEK-6 and MEK-7.

Also see MEK-2 Inhibitors for functional analysis of cellular responses to MEK-2.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
MEK-2 Antibody (N-20) sc-524 200 µg/ml $279
MEK-2 Antibody (N-20) AC sc-524 AC 500 µg/ml, 25% ag $366
MEK-2 (N-20) P sc-524 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MEK-2 siRNA (h) sc-35905 10 µM $258
MEK-2 siRNA (m) sc-35906 10 µM $258
MEK-2 (h)-PR sc-35905-PR 10 µM, 20 µl $23
MEK-2 (m)-PR sc-35906-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MEK-2 shRNA Plasmid (h) sc-35905-SH 20 µg $520
MEK-2 shRNA Plasmid (m) sc-35906-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MEK-2 shRNA (h) Lentiviral Particles sc-35905-V 200 µl $625
MEK-2 shRNA (m) Lentiviral Particles sc-35906-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
WEHI-231 Whole Cell Lysate sc-2213 500 µg/200 µl $104
MEK-2 (h3): 293T Lysate sc-158719 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MAP2K2 5605 19p13.3 NM_030662 P36507
 601263
Mouse Map2k2 26396 10 C1 Q63932
 N/A
 

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

MEK-2 Antibody (N-20) Product Citations
See how others have used MEK-2 Antibody (N-20) and or MEK-2 Antibody (N-20) conjugates.


21 total citations
Loading citations.
 
MEK-2 Antibody (N-20) Data
Click on image to enlarge
sc-524
MEK-2 (N-20): sc-524. Western blot analysis of MEK-2 expression in Jurkat (A), K-562 (B), NIH/3T3 (C) and WEHI-231 (D) whole cell lysates.
sc-524
MEK-2 (N-20): sc-524. Immunofluorescence staining of methanol-fixed K-562 cells showing cytoplasmic and membrane staining.
sc-524
MEK-2 (N-20): sc-524. Western blot analysis of MEK-2 expression in non-transfected 293T: sc-117752 (A), mouse MEK-2 transfected 293T: sc-121596 (B) and NIH/3T3 (C) whole cell lysates.
sc-524
MEK-2 (N-20): sc-524. Western blot analysis of MEK-2 expression in non-transfected 293T: sc-117752 (A), human MEK-2 transfected 293T: sc-158719 (B) and Jurkat (C) whole cell lysates.
sc-524
goat anti-rabbit IgG-HRP: sc-2030. Western blot analysis of MEK-2 expression in HeLa whole cell lysate. Antibody tested: MEK-2 (N-20): sc-524.
sc-524
goat anti-rabbit IgG-HRP: sc-2301. Western blot analysis of MEK-2 expression in HeLa whole cell lysate. Antibody tested: MEK-2 (N-20): sc-524.
sc-524
donkey anti-rabbit IgG-HRP: sc-2305. Western blot analysis of MEK-2 expression in Hela whole cell lysate. Antibody tested: MEK-2 (N-20): sc-524.
sc-524
donkey anti-rabbit IgG-HRP: sc-2317. Western blot analysis of MEK-2 expression in HeLa whole cell lysate. Antibody tested: MEK-2 (N-20): sc-524.
sc-524
bovine anti-rabbit IgG-HRP: sc-2379. Western blot analysis of MEK-2 expression in HeLa whole cell lysate. Antibody tested: MEK-2 (N-20): sc-524.
sc-524
bovine anti-rabbit IgG-HRP: sc-2385. Western blot analysis of MEK-2 expression in HeLa whole cell lysate. Antibody tested: MEK-2 (N-20): sc-524.
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