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home » Cell Cycle Proteins » Rbx Antibody / Rbx Antibodies » Rbx1 (N-16): sc-5201

Rbx1 (N-16) Antibody: sc-5201

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the N-terminus of Rbx1 of human origin
  • recommended for detection of Rbx1 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and avian
  • blocking peptide, sc-5201 P
 
Additional Rbx Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human RBX1 9978 22q13.2 NM_014248 P62877
 603814
Mouse Rbx1 56438 15 E1 P62878
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Rbx1 (N-16) sc-5201 200 µg/ml $279
Rbx1 (N-16) P sc-5201 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Rbx1 siRNA (h) sc-44072 10 µM $258
Rbx1 siRNA (m) sc-152766 10 µM $258
Rbx1 (h)-PR sc-44072-PR 10 µM $23
Rbx1 (m)-PR sc-152766-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Rbx1 shRNA Plasmid (h) sc-44072-SH 20 µg $520
Rbx1 shRNA Plasmid (m) sc-152766-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Rbx1 shRNA (h) Lentiviral Particles sc-44072-V 200 µl $625
Rbx1 shRNA (m) Lentiviral Particles sc-152766-V 200 µl $625

Rbx1 Background Information
Rbx1 (ROC1 and Hrt1) and the closely related protein Rbx2 (ROC2) are RING finger containing homologs of the yeast protein APC11, a member of the anaphase-promoting complex (APC) (1-4). Rbx1 was shown to be a component of the von Hippel-Lindau (VHL) transcription elongation complex, which includes VHL, Elongin B, Elongin C and Cullin-2 (1). Rbx1 interacts with Cullin-1 in the SCF (Skp1-Cdc53-F-box protein) ubiquitin ligase complex (2-4). Rbx1 functions as a common subunit of SCF complexes required for ubiquination of various proteins including yeast G1 cyclins, IkBa and b-catenin (2-4). Rbx1 was shown to enhance the ubiquitin ligase activity of the VHL/Cullin-2 complex, and of the SCF/Cullin-1 complex (5).

Rbx1 (N-16) Product Citations
See how others have used Rbx1 (N-16): sc-5201 antibody and or Rbx1 (N-16) antibody conjugates.


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