epitope mapping at the N-terminus of LBP-9 of human origin
recommended for detection of LBP-9 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including bovine, porcine and avian
TransCruz reagent for Gel Supershift and ChIP applications, sc-50831 X, 200 µg/0.1 ml
LBP-9 Background Information The long terminal repeat binding protein-1 (LBP-1) mammalian family of transcription factors are proteins that stimulate transcription in HeLa cells from the major late promoter of simian virus 40 in vitro. The two related human LBP-1 genes are TFCP2A, which encodes the alternatively spliced transcripts LBP-1a and LBP-1b, and TFCP2C, which encodes LBP-1c and LBP-1d. LBP-9, also designated transcription factor CP2-like 1 (TFCP2L1), is a protein of 479 amino acids. LBP-9 shows 83% sequence homology with LBP-1b and acts as a suppressor factor inhibiting the stimulation effect of LBP-1b. LBP-9 may regulate the P450scc reporter activity through the -155/-131 element.
