Welcome to Santa Cruz Biotechnology!
SCBT Home
Home » Structural Proteins » Parvin Antibodies » γ-parvin Antibody (N-19): sc-50769

γ-parvin Antibody (N-19): sc-50769

 |  Datasheet

(Based on data analysis)

  • γ-parvin Antibody (N-19) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the N-terminus of γ-parvin of human origin
  • recommended for detection of γ-parvin of human origin by WB, IP, IF and ELISA
  • blocking peptide, sc-50769 P
 

See additional Parvin Antibodies including Parvin, alpha-parvin, beta-parvin and gamma-parvin.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
γ-parvin Antibody (N-19) sc-50769 200 µg/ml $279
γ-parvin (N-19) P sc-50769 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
γ-parvin siRNA (h) sc-61302 10 µM $258
γ-parvin (h)-PR sc-61302-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
γ-parvin shRNA Plasmid (h) sc-61302-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
γ-parvin shRNA (h) Lentiviral Particles sc-61302-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
γ-parvin (h): 293T Lysate sc-114463 100 µg/200 µl $205
HL-60 Whole Cell Lysate sc-2209 500 µg/200 µl $104
γ-parvin (h2): 293T Lysate sc-129406 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PARVG 64098 22q13.31 NM_022141 Q9HBI0
 608122
 

The parvin family, including å-parvin, ∫-parvin and ©-parvin, link integrins and associated proteins with intracellular pathways, which regulate actin cytoskeletal dynamics and cell survival. All three family members localize to focal adhesions and function in cell adhesion, spreading, motility and survival through interactions with partners, such as integrin-linked kinase (ILK), paxillin, å-actinin and testicular kinase 1. å-parvin is widely expressed, with highest levels detected in the skeletal muscle, heart, liver and kidney. A complex made up of å-parvin, ILK and the LIM protein PINCH-1 is critical for cell survival in a variety of cells, including certain cancer cells, kidney podocytes and cardiac myocytes. ∫-parvin links initial integrin signals to rapid actin reorganization, thereby playing a critical role in fibroblast migration. The ILK-©-parvin complex is essential for the establishment of cell polarity required for leukocyte migration.
γ-parvin Antibody (N-19) Data
Click on image to enlarge
sc-50769
γ-parvin (N-19): sc-50769. Western blot analysis of γ-parvin expression in non-transfected: sc-117752 (A) and human γ-parvin transfected: sc-114463 (B) 293T whole cell lysates.
sc-50769
γ-parvin (N-19): sc-50769. Western blot analysis of γ-parvin expression in non-transfected 293T: sc-117752 (A), human γ-parvin transfected 293T: sc-129406 (B) and HL-60 (C) whole cell lysates.
sc-50769
γ-parvin (N-19): sc-50769. Western blot analysis of γ-parvin expression in non-transfected 293T: sc-117752 (A), human γ-parvin transfected 293T: sc-129407 (B) and HL-60 (C) whole cell lysates.
Download
Datasheets
Get Adobe Acrobat Reader