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γ-parvin Antibody (D-20): sc-50766

 |  Datasheet

(Based on data analysis)

  • γ-parvin Antibody (D-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of γ-parvin of mouse origin
  • recommended for detection of γ-parvin of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine
  • blocking peptide, sc-50766 P
 

See additional Parvin Antibodies including Parvin, alpha-parvin, beta-parvin and gamma-parvin.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
γ-parvin Antibody (D-20) sc-50766 200 µg/ml $279
γ-parvin (D-20) P sc-50766 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
γ-parvin siRNA (m) sc-61304 10 µM $258
γ-parvin siRNA (h) sc-61302 10 µM $258
γ-parvin (m)-PR sc-61304-PR 10 µM, 20 µl $23
γ-parvin (h)-PR sc-61302-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
γ-parvin shRNA Plasmid (m) sc-61304-SH 20 µg $520
γ-parvin shRNA Plasmid (h) sc-61302-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
γ-parvin shRNA (m) Lentiviral Particles sc-61304-V 200 µl $625
γ-parvin shRNA (h) Lentiviral Particles sc-61302-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PARVG 64098 22q13.2 NM_001137605, NM_001137606, NM_022141 NP_071424
 608122
Mouse Parvg 64099 15 E2 Q9ERD8
 N/A
 

The parvin family, including å-parvin, ∫-parvin and ©-parvin, link integrins and associated proteins with intracellular pathways, which regulate actin cytoskeletal dynamics and cell survival. All three family members localize to focal adhesions and function in cell adhesion, spreading, motility and survival through interactions with partners, such as integrin-linked kinase (ILK), paxillin, å-actinin and testicular kinase 1. å-parvin is widely expressed, with highest levels detected in the skeletal muscle, heart, liver and kidney. A complex made up of å-parvin, ILK and the LIM protein PINCH-1 is critical for cell survival in a variety of cells, including certain cancer cells, kidney podocytes and cardiac myocytes. ∫-parvin links initial integrin signals to rapid actin reorganization, thereby playing a critical role in fibroblast migration. The ILK-©-parvin complex is essential for the establishment of cell polarity required for leukocyte migration.
γ-parvin Antibody (D-20) Data
Click on image to enlarge
sc-50766
γ-parvin (D-20): sc-50766. Immunofluorescence staining of normal mouse spleen frozen section showing cytoplasmic staining.
sc-50766
γ-parvin (D-20): sc-50766. Western blot analysis of γ-parvin expression in non-transfected: sc-117752 (A) and human γ-parvin transfected: sc-114463 (B) 293T whole cell lysates.
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