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- goat polyclonal IgG, 200µg/ml
- epitope mapping near the N-terminus of NEIL3 of mouse origin
- recommended for detection of NEIL3 of mouse and, to a lesser extent, rat origin by WB, IP, IF and ELISA
- TransCruz reagent for Gel Supershift and ChIP applications, sc-50750 X, 200 µg/0.1 ml
- blocking peptide, sc-50750 P
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Ordering Information
Recommended Support Products:
(click button of application of choice)
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Mouse |
Neil3 |
234258 |
8 B1.3 |
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Q8K203
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N/A |
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NEIL3 Background Information
NEIL1, NEIL2 and NEIL3 (also known as endonuclease VIII-like 1,2 and 3 or DNA-(apurinic or apyrimidinic site) lyase NEIL 1, 2 and 3) are nuclear proteins involved in the repair of DNA damaged by oxidation. The NEIL proteins belong to the FPG family. They act as DNA glycosylases that can recognize and remove damaged bases, leaving an abasic site. NEIL3, however, lacks the proline resi-due at the N-terminus which acts as the active site residue found in NEIL1 and NEIL2. Thus, reports of NEIL3 DNA glycosylase activity are contradictory. NEIL3 localizes to the nucleus and only demonstrates expression in thymus and testis tissues. The deduced 605 amino acid NEIL3 protein contains both one FPG-type zinc finger and one RanBP2-type zinc finger. |
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NEIL3 (T-18)
Click on image to enlarge
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NEIL3 (T-18): sc-50750. Western blot analysis of mouse recombinant NEIL3 fusion protein.
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