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BMCP1 (UCP5) Antibody (Q-16): sc-50540

 |  Datasheet

(Based on data analysis)
  • BMCP1 (UCP5) Antibody (Q-16) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the C-terminus of BMCP1 (UCP5) of human origin
  • recommended for detection of BMCP1 (UCP5) reactive with all isoforms of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-50540 P
 

See additional BMCP Antibodies.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
BMCP1 (UCP5) Antibody (Q-16) sc-50540 200 µg/ml $279
BMCP1 (UCP5) (Q-16) P sc-50540 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
BMCP1 siRNA (h) sc-60275 10 µM $258
BMCP1 siRNA (m) sc-60276 10 µM $258
BMCP1 (h)-PR sc-60275-PR 10 µM, 20 µl $23
BMCP1 (m)-PR sc-60276-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
BMCP1 shRNA Plasmid (h) sc-60275-SH 20 µg $520
BMCP1 shRNA Plasmid (m) sc-60276-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
BMCP1 shRNA (h) Lentiviral Particles sc-60275-V 200 µl $625
BMCP1 shRNA (m) Lentiviral Particles sc-60276-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SLC25A14 9016 Xq25 NM_003951, NM_022810 O95258
 300242
Mouse Slc25a14 20523 X A4 Q9Z2B2
 N/A
 

Brain mitochondrial carrier protein 1 (BMCP1), also designated uncoupling protein 5 (UCP5) or solute carrier family 25 member 14 (SLC25A14), is a 325-amino acid, proton channel carrier protein not coupled to oxidative phosphorylation. It is located in the inner membrane of mitochondria and is linked to the generation of heat. Like other UCPs, BMCP1 facilitates the transfer of anions from the inner to the outer mitochondrial membrane as well as the return transfer of protons from the outer to the inner mitochondrial membrane. In addition, BMCP1 reduces the mitochondrial membrane potential in mammalian cells. BMCP1 is mainly expressed in the brain, while weaker expression is seen in the pituitary and testis. It contains 6 transmembrane domains, 3 motifs typical of mitochondrial energy transfer proteins, and 20 amino acids at the N terminus that are absent in UCP1, UCP2, and UCP3. The BMCP1 protein shares 34, 38, and 39% homology with UCP1, UCP2, and UCP3, respectively.