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Calpain 5 Antibody (H-105): sc-50500

 |  Datasheet

(Based on data analysis)

  • Calpain 5 Antibody (H-105) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 1-105 mapping at the N-terminus of Calpain 5 of human origin
  • recommended for detection of Calpain 5 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
 
Full-length Calpain 5 protein sequence with immunogen highlighted:
MFSCVKPYEDQNYSALRRDCRRRKVLFEDPLFPATDDSLYYKGTPGPAVRWKRPKGICEDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWEQEWDPEKPNAYAGIFHFHFWRFGEWVDVVIDDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDVRKVRLGHGLLAFFKSEKLDMIRLRNPWGEREWNGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRVINTSHLSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCGYPQLVTQVHVLGAAGLKDSPTGANSYVIIKCEGDKVRSAVQKGTSTPEYNVKGIFYRKKLSQPITVQVWNHRVLKDEFLGQVHLKADPDNLQALHTLHLRDRNSRQPSNLPGTVAVHILSSTSLMAV

See additional Calpain Antibodies including Calpain, Calpain 1, Calpain reg, Calpain 2, Calpain 3, Calpain 5, Calpain 6, Calpain 7, Calpain 8, Calpain 9, Calpain 10, Calpain 11, Calpain 12, Calpain 13 and Calpain 15.

Also see Calpain Inhibitors for functional analysis of cellular responses to Calpain.


Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Calpain 5 Antibody (H-105) sc-50500 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Calpain 5 siRNA (h) sc-62064 10 µM $258
Calpain 5 siRNA (m) sc-62065 10 µM $258
Calpain 5 (h)-PR sc-62064-PR 10 µM, 20 µl $23
Calpain 5 (m)-PR sc-62065-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Calpain 5 shRNA Plasmid (h) sc-62064-SH 20 µg $520
Calpain 5 shRNA Plasmid (m) sc-62065-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Calpain 5 shRNA (h) Lentiviral Particles sc-62064-V 200 µl $625
Calpain 5 shRNA (m) Lentiviral Particles sc-62065-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Calpain 5 (h): 293T Lysate sc-113177 100 µg/200 µl $205
Calpain 5 (m): 293T Lysate sc-126572 100 µg/200 µl $205
TF-1 Cell Lysate sc-2412 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CAPN5 726 11q13.5 NM_004055 O15484
 602537
Mouse Capn5 12337 7 E2 O08688
 N/A
 

Calpains are calcium-activated thiol proteases involved in intracellular processing of proteins and signal transduction. The classic calpains are hetero-dimers with one large subunit, one small subunit and five EF-hand-calcium binding structures. The large subunit varies between family members and can be active without the small subunit. Calpain 5, sometimes referred to as HTRA3, belongs to the non-classical calpain subfamily that lacks the EF-hand-calcium-binding structures. Calpain 5 is ubiquitously expressed, localizes to the cytoplasm and nucleus and is a homolog of Calpain 10. Calpain 5, in addition to Calpain 10 and Calpain 6, differs from other subfamily members by the presence of a T-domain that is homologous to the Caenorhabditis elegans protein Tra-3. Calpain 5, the human ortholog of this nematode protein, may play a role in sex determination.
Calpain 5 Antibody (H-105) Data
Click on image to enlarge
sc-50500
Calpain 5 (H-105): sc-50500. Western blot analysis of human recombinant Calpain 5 fusion protein.
sc-50500
Calpain 5 (H-105): sc-50500. Western blot analysis of Calpain 5 expression in TF-1 whole cell lysate.
sc-50500
Calpain 5 (H-105): sc-50500. Western blot analysis of Calpain 5 expression in non-transfected: sc-117752 (A) and mouse Calpain 5 transfected: sc-126572 (B) 293T whole cell lysates.
sc-50500
Calpain 5 (H-105): sc-50500. Western blot analysis of Calpain 5 expression in non-transfected: sc-117752 (A) and human Calpain 5 transfected: sc-113177 (B) 293T whole cell lysates.
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