epitope corresponding to amino acids 159-223 mapping within an internal region of VGF of human origin
recommended for detection of VGF of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine and equine
VGF Background Information Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.
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VGF (H-65)
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VGF (H-65): sc-50407. Western blot analysis of VGF expression in NGF treated PC-12 whole cell lysate.
