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home » Signaling Intermediates » Paip Antibody / Paip Antibodies » Paip1 (H-300): sc-50364

Paip1 (H-300) Antibody: sc-50364

  |  Datasheet
  • rabbit polyclonal IgG, 200µg/ml
  • epitope corresponding to amino acids 180-479 mapping at the C-terminus of Paip1 of human origin
  • recommended for detection of Paip1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
 
Additional Paip Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PAIP1 10605 5p12 NM_006451, NM_182789, NM_183323 Q9H074
 605184
Mouse Paip1 218693 13 D2.3 Q8VE62
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Paip1 (H-300) sc-50364 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Paip1 siRNA (h) sc-40800 10 µM $258
Paip1 siRNA (m) sc-40801 10 µM $258
Paip1 (h)-PR sc-40800-PR 10 µM $23
Paip1 (m)-PR sc-40801-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Paip1 shRNA Plasmid (h) sc-40800-SH 20 µg $520
Paip1 shRNA Plasmid (m) sc-40801-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Paip1 shRNA (h) Lentiviral Particles sc-40800-V 200 µl $625
Paip1 shRNA (m) Lentiviral Particles sc-40801-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
Paip1 (h): 293 Lysate sc-112247 100µg/200µl $205
Paip1 (m): 293T Lysate sc-122357 100µg/200µl $205
Paip1 (h): 293T Lysate sc-171347 100µg/200µl $205
Paip1 (h2): 293T Lysate sc-172162 100µg/200µl $205

Paip1 Background Information
Paip, for PABP-interacting protein, binds to the polyadenylate-binding protein (PABP), which in yeasts and plants has been shown to bind to the eukaryotic initiation factor component eIF4G. There are two Paip proteins called Paip1 and Paip2. Paip1 stimulates translation, and Paip2, which competes with Paip1 for binding to PABP, represses translation. Paip2 decreases the affinity of PABP for polyadenylate RNA, and disrupts the repeating structure of poly(A) ribonucleoprotein. Paip1 contains an eIF4A-binding region and a proline-rich N terminus. Overexpression of Paip1 in COS-7 cells stimulates translation, perhaps by providing a physical link between the mRNA termini. The human Paip1 gene encodes a 480 amino acid protein.
Paip1 (H-300)
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sc-50364
Paip1 (H-300): sc-50364. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic and nuclear localization.
sc-50364
Paip1 (H-300): sc-50364. Western blot analysis of Paip1 expression in Paip1 transfected: sc-112247 (A) and non-transfected: sc-110760 (B) 293 whole cell lysates.
sc-50364
Paip1 (H-300): sc-50364. Western blot analysis of Paip1 expression in non-transfected: sc-117752 (A) and truncated mouse Paip1 transfected: sc-122357 (B) 293T whole cell lysates.
sc-50364
Paip1 (H-300): sc-50364. Western blot analysis of Paip1 expression in non-transfected 293T: sc-117752 (A), human Paip1 transfected 293T: sc-172162 (B) and HeLa (C) whole cell lysates.
sc-50364
Paip1 (H-300): sc-50364. Western blot analysis of Paip1 expression in non-transfected 293T: sc-117752 (A), human Paip1 transfected 293T: sc-171347 (B) and HeLa (C) whole cell lysates.
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