Welcome to Santa Cruz Biotechnology!
SCBT Home
Home » Synthesis and Degradation » NDUFS Antibodies » NDUFS1 Antibody (D-20): sc-50131

NDUFS1 Antibody (D-20): sc-50131

 |  Datasheet

(Based on data analysis)

  • NDUFS1 Antibody (D-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of NDUFS1 of human origin
  • recommended for detection of NDUFS1 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-50131 P
  • See 1 citations for NDUFS1 Antibody (D-20)
 

See additional NDUFS Antibodies including NDUFS, NDUFS1, NDUFS2, NDUFS4, NDUFS6, NDUFS7, NDUFS5 and NDUFS8.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
NDUFS1 Antibody (D-20) sc-50131 200 µg/ml $279
NDUFS1 (D-20) P sc-50131 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
NDUFS1 siRNA (h) sc-61164 10 µM $258
NDUFS1 siRNA (m) sc-61165 10 µM $258
NDUFS1 (h)-PR sc-61164-PR 10 µM, 20 µl $23
NDUFS1 (m)-PR sc-61165-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
NDUFS1 shRNA Plasmid (h) sc-61164-SH 20 µg $520
NDUFS1 shRNA Plasmid (m) sc-61165-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
NDUFS1 shRNA (h) Lentiviral Particles sc-61164-V 200 µl $625
NDUFS1 shRNA (m) Lentiviral Particles sc-61165-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
mouse heart extract sc-2254 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human NDUFS1 4719 2q33.3 NM_005006 P28331
 252010
Mouse Ndufs1 227197 1 C2 Q91VD9
 N/A
 

The multisubunit NADH:ubiquinone oxidoreductase (complex I) is the first enzyme complex in the electron transport chain of mitochondria. Through use of chaotropic agents, complex I can be separated into 3 different fractions: a flavoprotein fraction, an iron-sulfur protein (IP) fraction, and a hydrophobic protein (HP) fraction. The IP fraction contains NDUFS1-7. NDUFS1, a 75kD protein, is the largest subunit of complex I, and is thought to be the first of the Fe-S proteins to accept electrons from an NADH-flavoprotein reductase within the complex. NDUFS1 may even form part of the active site crevice where NADH is oxidized. NDUFS1 is also a critical caspase substrate in mitochondria, and caspase cleavage of NDUFS1 is required for several mitochondrial changes associated with apoptosis.

NDUFS1 Antibody (D-20) Product Citations
See how others have used NDUFS1 Antibody (D-20) and or NDUFS1 Antibody (D-20) conjugates.


1 total citations
Loading citations.
 
NDUFS1 Antibody (D-20) Data
Click on image to enlarge
sc-50131
NDUFS1 (D-20): sc-50131. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
Download
Datasheets
Get Adobe Acrobat Reader