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ITM2A Antibody (N-15): sc-50022

 |  Datasheet

(Based on data analysis)
  • ITM2A Antibody (N-15) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the N-terminus of ITM2A of human origin
  • recommended for detection of ITM2A (Integral membrane protein 2A) of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine and porcine
  • blocking peptide, sc-50022 P
 

See additional ITM2 Antibodies including ITM2, ITM2C, ITM2A and ITM2B.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
ITM2A Antibody (N-15) sc-50022 200 µg/ml $279
ITM2A (N-15) P sc-50022 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ITM2A siRNA (h) sc-60867 10 µM $258
ITM2A siRNA (m) sc-60868 10 µM $258
ITM2A (h)-PR sc-60867-PR 10 µM, 20 µl $23
ITM2A (m)-PR sc-60868-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ITM2A shRNA Plasmid (h) sc-60867-SH 20 µg $520
ITM2A shRNA Plasmid (m) sc-60868-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ITM2A shRNA (h) Lentiviral Particles sc-60867-V 200 µl $625
ITM2A shRNA (m) Lentiviral Particles sc-60868-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ITM2A 9452 Xq21.1 NM_004867 O43736
 300222
Mouse Itm2a 16431 X D Q61500
 N/A
 

The type II integral membrane (ITM2) protein family consists of three members ITM2A (also designated E25), ITM2B and ITM2C. ITM2A expression is high in osteogenic and lymphoid tissues, while both ITM2B and ITM2C are expressed in brain. Mutations in the ITM2B gene can lead to familial British dementia (fbd), and autosomal dominant disease characterized by progressive dementia, spasticity, and cerebellar ataxia, or familial Danish dementia (fdd), an autosomal dominant disorder characterized by cataracts, deafness, progressive ataxia, and dementia. The ITM2A 263-amino acid protein contains an N-terminal cytosolic domain, an uncleaved signal anchor sequence, and a tyrosine-rich C-terminal domain. Human ITM2A shares 91% homology with mouse ITM2A.