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DUOX2 Antibody (Y-15): sc-49939

 |  Datasheet

(Based on data analysis)
  • DUOX2 Antibody (Y-15) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of DUOX2 of human origin
  • recommended for detection of DUOX2 (Dual oxidase 2) of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including bovine
  • blocking peptide, sc-49939 P
  • See 1 citations for DUOX2 Antibody (Y-15)
 

See additional DUOX Antibodies including DUOX, DUOX1, DUOXA1, DUOX2 and DUOXA2.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
DUOX2 Antibody (Y-15) sc-49939 200 µg/ml $279
DUOX2 (Y-15) P sc-49939 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DUOX2 siRNA (h) sc-60552 10 µM $258
DUOX2 siRNA (m) sc-60553 10 µM $258
DUOX2 (h)-PR sc-60552-PR 10 µM, 20 µl $23
DUOX2 (m)-PR sc-60553-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DUOX2 shRNA Plasmid (h) sc-60552-SH 20 µg $520
DUOX2 shRNA Plasmid (m) sc-60553-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DUOX2 shRNA (h) Lentiviral Particles sc-60552-V 200 µl $625
DUOX2 shRNA (m) Lentiviral Particles sc-60553-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human DUOX2 50506 15q21.1 NM_014080 Q9NRD8
 607200
Mouse Duox2 214593 2 E5 NP_808278
 N/A
 

Dual oxidase 1 (DUOX1), a homolog of glycoprotein p91phox, is expressed in airway epithelium and generates reactive oxygen species (ROS). Dual oxidase 2 (DUOX2), also designated NADPH thyroid oxidase 2, p138 thyroid oxidase or large NOX2, localizes to the apical membrane of epithelial cells. DUOX1, also designated NADPH thyroid oxidase or large NOX1, and DUOX2 are multi-pass membrane proteins predominantly expressed in thyrocytes, tracheal surface epithelial cells as well as thyroid, colon, duodenum, trachea and bronchium. DUOX1 and DUOX2 generate hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. In mucosa, DUOX proteins are involved in thyroid hormone biosynthesis and lactoperoxidase-mediated antimicrobial defense. Defects in the gene encoding for DUOX2 cause congenital hypothyroidism (CH), a disorder characterized by a defect in hydrogen peroxide production in the thyroid gland.

DUOX2 Antibody (Y-15) Product Citations
See how others have used DUOX2 Antibody (Y-15) and or DUOX2 Antibody (Y-15) conjugates.


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