santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » Transcription Regulators » CPEB Antibody / CPEB Antibodies » CPEB (K-16): sc-48983

CPEB (K-16) Antibody: sc-48983

  |  Datasheet
  • goat polyclonal IgG, 200µg/ml
  • epitope mapping near the C-terminus of CPEB of human origin
  • recommended for detection of CPEB long and short isoforms of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-48983 X, 200 µg/0.1 ml
  • blocking peptide, sc-48983 P
 
Additional CPEB Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CPEB1 64506 15q25.2 NM_030594 Q9BZB8
 607342
Mouse Cpeb1 12877 7 D3 P70166
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CPEB (K-16) sc-48983 200 µg/ml $279
CPEB (K-16) P sc-48983 P
(peptide)
 100 µg/0.5 ml $61
CPEB (K-16) X sc-48983 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CPEB siRNA (h) sc-37755 10 µM $258
CPEB siRNA (m) sc-37756 10 µM $258
CPEB (h)-PR sc-37755-PR 10 µM $23
CPEB (m)-PR sc-37756-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CPEB shRNA Plasmid (h) sc-37755-SH 20 µg $520
CPEB shRNA Plasmid (m) sc-37756-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CPEB shRNA (h) Lentiviral Particles sc-37755-V 200 µl $625
CPEB shRNA (m) Lentiviral Particles sc-37756-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CPEB (h2): 293T Lysate sc-116291 100µg/200µl $205
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
IMR-32 Cell Lysate sc-2409 500 µg/200 µl $104
mouse brain extract sc-2253 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104

CPEB Background Information
The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, one mechanism of controlling translation, is driven by cytoplasmic polyadenylation element binding protein, CPEB. CPEB is a highly conserved, sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element, thereby modulating translational repression and mRNA localization. Blocking cytoplasmic polyadenylation by interfering with the CPE or CPEB prevents the translational activation and translational repression of mRNAs crucial for oocyte maturation. CPEB is synthesized during oogenesis and stockpiled in the oocyte. CPEB degradation occurs via the proteasome pathway, most likely through ubiquitin-conjugated intermediates.

CPEB (K-16)
Click on image to enlarge
sc-48983
CPEB (K-16): sc-48983. Western blot analysis of CPEB expression in HeLa (A), NIH/3T3 (B) and IMR-32 (C) whole cell lysates and rat ovary (D) and mouse brain (E) tissue extracts.
sc-48983
CPEB (K-16): sc-48983. Western blot analysis of CPEB expression in HeLa whole cell lysate.
sc-48983
CPEB (K-16): sc-48983. Western blot analysis of CPEB expression in non-transfected 293T: sc-117752 (A), human CPEB transfected 293T: sc-116291 (B) and HeLa (C) whole cell lysates.
sc-48983
CPEB (K-16): sc-48983. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
Download
Datasheets
Get Adobe Acrobat Reader