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ALDH2 Antibody (N-14): sc-48838

 |  Datasheet

(Based on data analysis)

  • ALDH2 Antibody (N-14) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of ALDH2 of human origin
  • recommended for detection of ALDH2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine and porcine
  • blocking peptide, sc-48838 P
 

See additional ALDH Antibodies including ALDH, ALDH1, ALDH1A7, ALDH2, ALDH1A1, ALDH1B1, ALDH1L1, ALDH1A2, ALDH1L2, ALDH1A3, ALDH3A1, ALDH3B1, ALDH3A2, ALDH3B2, ALDH4A1, ALDH5A1, ALDH6A1, ALDH8A1, ALDH9A1, ALDH16A1 and ALDH18A1.

Also see ALDH Inhibitors for functional analysis of cellular responses to ALDH.


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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
ALDH2 Antibody (N-14) sc-48838 200 µg/ml $279
ALDH2 (N-14) P sc-48838 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ALDH2 siRNA (h) sc-60147 10 µM $258
ALDH2 siRNA (m) sc-60148 10 µM $258
ALDH2 (h)-PR sc-60147-PR 10 µM, 20 µl $23
ALDH2 (m)-PR sc-60148-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ALDH2 shRNA Plasmid (h) sc-60147-SH 20 µg $520
ALDH2 shRNA Plasmid (m) sc-60148-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ALDH2 shRNA (h) Lentiviral Particles sc-60147-V 200 µl $625
ALDH2 shRNA (m) Lentiviral Particles sc-60148-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
rat liver extract sc-2395 500 µg/200 µl $104
mouse lung extract sc-2390 500 µg/200 µl $104
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
ALDH2 (m): 293T Lysate sc-118342 100 µg/200 µl $205
ALDH2 (h): 293 Lysate sc-158255 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ALDH2 217 12q24.12 NM_000690 P05091
100650
Mouse Aldh2 11669 5 F P47738
N/A
 


Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1); aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase cytosolic; ALDHII; ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). The major liver isoform ALDH1 localizes to cytosolic space, while ALDH2 localizzes to the mitochondria. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH2 is present in most Caucasians, yet is absent in 50% of Asians. The absence of this enzyme has been linked to alcohol intolerance; and thusly, a reduced risk for alcoholism-related liver disease.

ALDH2 Antibody (N-14) Data
Click on image to enlarge
ALDH2 (N-14): sc-48838. Western blot analysis of ALDH2 expression in rat liver tissue extract.
ALDH2 (N-14): sc-48838. Western blot analysis of ALDH2 expression in non-transfected 293T: sc-117752 (A), human ALDH2 transfected 293T: sc-118342 (B) and c4 (C) whole cell lysates.
ALDH2 (N-14): sc-48838. Western blot analysis of ALDH2 expression in non-transfected: sc-110760 (A) and human ALDH2 transfected: sc-158255 (B) 293 whole cell lysates and rat liver tissue extract (C).
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