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USP6/32 Antibody (K-14): sc-48694

 |  Datasheet

(Based on data analysis)

  • USP6/32 Antibody (K-14) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of USP6 of human origin
  • recommended for detection of USP6 and USP32 of human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and avian
  • blocking peptide, sc-48694 P
 

See additional USP Antibodies including USP, USP1, USP17, USP27, USP46, USP2, USP3, USP4, USP5, USP6, USP9, USP9X, USP9Y, USP10, USP11, USP12, USP13, USP14, USP15, USP18, USP19, USP20, USP21, USP22, USP24, USP25, USP26, USP28, USP29, USP30, USP31, USP32, USP33, USP34, USP35, USP36, USP37, USP38, USP39, USP40, USP42, USP43, USP44, USP45, USP47, USP48, USP49, USP50, USP51, USP52, USP53, USP54 and USP17L4.

Also see USP Inhibitors for functional analysis of cellular responses to USP.


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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
USP6/32 Antibody (K-14) sc-48694 200 µg/ml $279
USP6/32 (K-14) P sc-48694 P
(peptide)
100 µg/0.5 ml $61
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human USP6 9098 17p13.2 XM_001134439 P35125
Human USP32 84669 17q23.2 Q8NFA0
607740
 


Ubiquitin-specific protease (USP6) is a 1,406 amino acid protein that is very hydrophilic and has two charge clusters that are characteristic of nucleic acid-binding regions. The USP6 gene is oncogenic and originated from the chimeric fusion of two genes: USP32 and TBC1D3. USP32 is an ancient, highly conserved gene, whereas the TBC1D3 gene came from a relatively recent segmental duplication. This duplication is absent in most other mammals and shows rapid amplification and propagation throughout the primate lineage. The chimeric USP6, however, only exists in the hominoid lineage of primates, so it may have contributed to hominoid speciation. USP6 is testis-specific, suggesting an implication in the emergence of reproductive barriers.