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home » Tumor Suppressors/Apoptosis » TACC Antibody / TACC Antibodies » TACC3 (D-2): sc-48368

TACC3 (D-2) Antibody: sc-48368

  |  Datasheet
  • mouse monoclonal IgG1, 200µg/ml
  • raised against amino acids 1-300 of TACC3 of human origin
  • recommended for detection of TACC3 of human origin by WB, IP, PAR, ELISA
 
Additional TACC Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TACC3 10460 4p16.3 NM_006342 Q9Y6A5
 605303
Mouse Tacc3 21335 5 B2 Q9JJ11
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
TACC3 (D-2) sc-48368 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TACC3 siRNA (h) sc-36602 10 µM $258
TACC3 siRNA (m) sc-36603 10 µM $258
TACC3 (h)-PR sc-36602-PR 10 µM $23
TACC3 (m)-PR sc-36603-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TACC3 shRNA Plasmid (h) sc-36602-SH 20 µg $520
TACC3 shRNA Plasmid (m) sc-36603-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TACC3 shRNA (h) Lentiviral Particles sc-36602-V 200 µl $625
TACC3 shRNA (m) Lentiviral Particles sc-36603-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
HL-60 Whole Cell Lysate sc-2209 500 µg/200 µl $104
TACC3 (h): 293T Lysate sc-111721 100µg/200µl $205
TACC3 (m): 293T Lysate sc-123890 100µg/200µl $205
TACC3 (m2): 293T Lysate sc-123891 100µg/200µl $205

TACC3 Background Information
TACC1 (transforming acidic coiled coil gene 1) is one of three TACC family members, which are thought to be involved in breast tumorigenesis. TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 8, 10, and 4. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
TACC3 (D-2)
Click on image to enlarge
sc-48368
TACC3 (D-2): sc-48368. Western blot analysis of TACC3 expression in HeLa (A), Jurkat (B) and HL-60 (C) whole cell lysates.
sc-48368
TACC3 (D-2): sc-48368. Immunoperoxidase staining of formalin fixed, paraffin-embedded human tonsil tissue showing cytoplasmic staining of follicle cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
sc-48368
TACC3 (D-2): sc-48368. Western blot analysis of TACC3 expression in non-transfected 293T: sc-117752 (A), human TACC3 transfected 293T: sc-111721 (B) and HeLa (C) whole cell lysates.
sc-48368
TACC3 (D-2): sc-48368. Western blot analysis of TACC3 expression in non-transfected 293T: sc-117752 (A), mouse TACC3 transfected 293T: sc-123890 (B) and Jurkat (C) whole cell lysates.
sc-48368
TACC3 (D-2): sc-48368. Western blot analysis of TACC3 expression in non-transfected 293T: sc-117752 (A), mouse TACC3 transfected 293T: sc-123891 (B) and HeLa (C) whole cell lysates.
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