santa cruz biotechnology, inc.

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- mouse monoclonal IgG2a; 200 µg/ml
- raised against amino acids 128-267 of IRF-4 of human origin
- recommended for detection of IRF-4 of mouse and human origin by WB, IP, IF and ELISA
- TransCruz reagent for Gel Supershift and ChIP applications, sc-48338 X, 200 µg/0.1 ml
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Ordering Information
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
IRF4 |
3662 |
6p25.3 |
NM_002460 |
Q15306
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601900 |
| Mouse |
Irf4 |
16364 |
13 A3.2 |
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Q64287
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N/A |
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IRF-4 Background Information Interferon regulatory factor-4 (IRF-4) belongs to the IRF family of DNA-binding factors which regulate both interferon and interferon-inducible genes. Family members include IRF-1–7, ISGF-3© p48 and IFN consensus sequence-binding protein (ICSBP). IRF-4 is also known as lymphocyte specific interferon regulatory factor (LSIRF), multiple myeloma oncogene 1 and PU.1 interaction partner (Pip). A nuclear protein specific to lymphoid cells, IRF-4 is a transcriptional activator that binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. |
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IRF-4 (F-4)
Click on image to enlarge
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IRF-4 (F-4): sc-48338. Western blot analysis of IRF-4 expression in Ramos (A) and MM-142 (B) nuclear extracts.
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