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home » Transcription Regulators » PRDM Antibody / PRDM Antibodies » PRDM8 (N-16): sc-48277

PRDM8 (N-16) Antibody: sc-48277

  |  Datasheet
  • goat polyclonal IgG, 200µg/ml
  • epitope mapping at the N-terminus of PRDM8 of human origin
  • recommended for detection of PRDM8 of mouse and human origin by WB, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-48277 X, 200 µg/0.1 ml
  • blocking peptide, sc-48277 P
 
Additional PRDM Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PRDM8 56978 4q21.21 NM_020226 Q9NQV8
 n/a
Mouse Prdm8 77630 5 E3 Q8BZ97
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
PRDM8 (N-16) sc-48277 200 µg/ml $279
PRDM8 (N-16) P sc-48277 P
(peptide)
 100 µg/0.5 ml $61
PRDM8 (N-16) X sc-48277 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PRDM8 siRNA (h) sc-61399 10 µM $258
PRDM8 siRNA (m) sc-61400 10 µM $258
PRDM8 (h)-PR sc-61399-PR 10 µM $23
PRDM8 (m)-PR sc-61400-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PRDM8 shRNA Plasmid (h) sc-61399-SH 20 µg $520
PRDM8 shRNA Plasmid (m) sc-61400-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PRDM8 shRNA (h) Lentiviral Particles sc-61399-V 200 µl $625
PRDM8 shRNA (m) Lentiviral Particles sc-61400-V 200 µl $625

PRDM8 Background Information
Usually, two products are produced from a PR-domain family member; these products differ by the presence or absence of the PR domain. The PR-plus product is underexpressed or disrupted, whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, which is a result of either genetic or epigenetic events, appears to be an determining cause of malignancy. PRDM8 in particular is thought to be involved in transcriptional regulation. Its subcellular location is the nucleus and research indicates that PRDM8 contains three C2H2-type zinc fingers and one SET domain.