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home » Neurobiology » PACSIN Antibody / PACSIN Antibodies » PACSIN3 (K-16): sc-48255

PACSIN3 (K-16) Antibody: sc-48255

  |  Datasheet
  • goat polyclonal IgG, 200µg/ml
  • epitope mapping within an internal region of PACSIN3 of human origin
  • recommended for detection of PACSIN3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-48255 P
 
Additional PACSIN Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PACSIN3 29763 11p11.2 NM_016223 Q9UKS6
 606513
Mouse Pacsin3 80708 2 E1 Q99JB8
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
PACSIN3 (K-16) sc-48255 200 µg/ml $279
PACSIN3 (K-16) P sc-48255 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PACSIN3 siRNA (h) sc-61279 10 µM $258
PACSIN3 siRNA (m) sc-61280 10 µM $258
PACSIN3 (h)-PR sc-61279-PR 10 µM $23
PACSIN3 (m)-PR sc-61280-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PACSIN3 shRNA Plasmid (h) sc-61279-SH 20 µg $520
PACSIN3 shRNA Plasmid (m) sc-61280-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PACSIN3 shRNA (h) Lentiviral Particles sc-61279-V 200 µl $625
PACSIN3 shRNA (m) Lentiviral Particles sc-61280-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PACSIN3 (m): 293T Lysate sc-127289 100µg/200µl $205
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104

PACSIN3 Background Information
PACSINs are a family of cytoplasm-resisdent phosphoproteins that aid in vesicle formation and transport. It is presumed that all isoforms oligomerize and bind dynamin, synaptojanin 1 and N-WASP through their Src homology 3 domains. Furthermore, PACSINs colocalize with dynamin, but not with clathrin, indicating that the proteins may play a specific role with a defined population of dynamin at distinct cellular locations. PACSIN3 (Protein Kinase C and Casein Kinase Substrate in Neurons 3) contains a short proline-rich region and lacks asparagine-proline-phenylalanine motifs, which differentiates it from the rest of the PACSIN family. Sequence analysis of cDNAs encoding mouse and human PACSIN3 predict that the human protein consists of 424-amino acids and is 94% identical to the mouse protein. Studies of the mouse protein report predominant expression in mouse lung, skeletal muscle, and heart as well as in brain, kidney, and uterus.

PACSIN3 (K-16)
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sc-48255
PACSIN3 (K-16): sc-48255. Western blot analysis of PACSIN3 expression in non-transfected: sc-117752 (A) and mouse PACSIN3 transfected: sc-127289 (B) 293T whole cell lysates.
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