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- goat polyclonal IgG, 200µg/ml
- epitope mapping near the N-terminus of NEIL1 of human origin
- recommended for detection of NEIL1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine and porcine
- TransCruz reagent for Gel Supershift and ChIP applications, sc-47611 X, 200 µg/0.1 ml
- blocking peptide, sc-47611 P
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Ordering Information
Recommended Support Products:
(click button of application of choice)
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
NEIL1 |
79661 |
15q24.2 |
NM_024608 |
Q96FI4
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608844 |
| Mouse |
Neil1 |
72774 |
9 B |
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Q8K4Q6
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N/A |
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NEIL1 Background Information
NEIL1, NEIL2 and NEIL3, also known as Endonuclease VIII-like 1,2 and 3 or DNA-(apurinic or apyrimidinic site) lyase NEIL 1, 2 and 3, are nuclear proteins involved in the repair of DNA damaged by oxidation. The NEIL proteins belong to the FPG familiy of proteins. They act as DNA glycosylases that can recognize and remove damaged bases, leaving an abasic site. NEIL3, however, lacks the proline residue at the N-terminus which acts as the active site residue found in NEIL1 and NEIL2. NEIL1 is a ubiquitiously expressed protein that is up-regulated during S-phase. NEIL2 is expressed primarily in testis, heart, skeletal muscle, placenta, brain, kidney and liver while NEIL3 is detected primarily in thymus and testis. |
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NEIL1 (S-17)
Click on image to enlarge
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NEIL1 (S-17): sc-47611. Western blot analysis of NEIL1 expression in non-transfected 293: sc-110760 (A), human NEIL1 transfected 293: sc-111234 (B) and HeLa (C) whole cell lysates. |
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