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- goat polyclonal IgG, 200µg/ml
- epitope mapping at the N-terminus of MYH10 of human origin
- recommended for detection of MYH10 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and avian
- blocking peptide, sc-47205 P
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Ordering Information
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
MYH10 |
4628 |
17p13.1 |
NM_005964 |
P35580
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160776 |
| Mouse |
Myh10 |
77579 |
11 B3 |
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Q61879
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N/A |
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MYH10 Background Information
Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer of two heavy chains (abbreviated as MYH or MHC) and four light chains (MLC) that interacts with Actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. MYH10 is also designated Myosin IIb, Myosin-10, NMMHC-IIB, nonmuscle myosin heavy chain IIb or cellular myosin heavy chain, type B. MYH10 is involved in cell shape, cytokinesis and specialized functions such as capping and secretion. It is expressed in leukoctyes and in glomeruli in the kidney.
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MYH10 (N-17)
Click on image to enlarge
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MYH10 (N-17): sc-47205. Western blot analysis of MYH10 expression in A10 (A), IMR-32 (B) and SK-N-SH (C) whole cell lysates and rat brain (D) and mouse brain (E) tissue extracts.
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